Basic Information | |
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Species | Panicum virgatum |
Cazyme ID | Pavirv00061408m |
Family | GT24 |
Protein Properties | Length: 1629 Molecular Weight: 183644 Isoelectric Point: 5.5061 |
Chromosome | Chromosome/Scaffold: 001246 Start: 6126 End: 22350 |
Description | UDP-glucose:glycoprotein glucosyltransferases;transferases, transferring hexosyl groups;transferases, transferring glycosyl groups |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT24 | 1324 | 1571 | 0 |
INIFSVASGHLYERFLKIMILSVLKKTQRPVKFWFIKNYLSPQFKDVIPHMAQEYGFEYELITYKWPTWLHKQKEKQRIIWAYKILFLDVIFPLSLRKVI FVDADQIVRADMGELYDMNLKGRPLAYTPFCDNNKDMDGYRFWKQGFWKDHLRGRPYHISALYVVDLAKFRQTAAGDTLRVFYEQLSKDPNSLSNLDQDL PNYAQHTVPIFSLPQEWLWCESWCGNATKARAKTIDLCNNPMTKEPKL |
Full Sequence |
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Protein Sequence Length: 1629 Download |
MAAARGARSG VSAAAAVLVS VLLVGGLASG GAGAEIRRQK NVQVALRAKW AGTPLLLEAS 60 ELLSKERKDL FWDFVNHWKE LDKGSECLTA KCCAQKIVED ARTLLNEPLS SIFEFSLTLR 120 SASPRLVLYR QLAEESLSSV SIKDSPGQIS GHGTGENFDE AVGPNSSGGT CCWVDTGNVL 180 LFNSADLHEW LEGLGKLAVD STEQPELFDF DHVYPRANIT APVAIFYGAV GTKCFKELHV 240 QLAEASKQGK VRYALRPVLP SGCQATSSFC GSIGALDAVT LSGYGVELAL KNMEYKAMDD 300 TAIKKGVPLE DPKTEDLSQE VRGFIFSKIL ERKPELNAEI MAFRDYLLSS TVSDTLEVWE 360 LKDLGHQTAQ RIVQASDPLQ SMQEINQNFP SIVSSLSRMK LDNSIKDEII ANQRMVPPGK 420 SLMALNGALI NIEDLDLYLL MDMVHGELSL ADQFARLKLP QSAARKILSA PPPAESNSFR 480 VDFRSSHVHY LNNLEEDDMY RRWRSNIQEL LMPVFPGQMR YIRKNLFHAV YVFDPASACG 540 AEASLSLTSL NFLFFTIDMV LSLYQDNVPI RFGIVMYSSR LINVIEESDG SLPLNDGEDT 600 SILITRLFLY IKETYSTQLA FEFLSNIHKS RNGEDYYSED LIEAHHVEGA FVDSLLSSAK 660 SHPQDVLLKL QKDNMYKEEA EQSSRFVHKL GLYKLQCCLL MNGLVHESNE DATMNAMNDE 720 LPRIQEQVYY GHIQSHTDVL EKFLSESSYK RYNPSITGKS AVKKFVSLFA SYHQEDSVFN 780 DMKYLQSPGT ADDAKPVTHL LAIDLSSKVG TKLLHEAISY LMDGTDRARV GLLLYVRSGC 840 SPPILLLKDI FDRTISSFSY KEKVLVFLHE LLKFYEAQPT PASSVAGDDW TRTMMEMVYS 900 LAAETALPVD DYKAWFKSFS ADTVPKGMDK LSDFLFGQLG LVFGSNAVIT NGRVFVMNEG 960 EPFLANDLGL LESMEYDLRT KYIFEIIEEV EFAGLDPDDM TSQFYSDIAM LVSSSMSVRE 1020 RPSERAHFEI LHAEHSAIKL NNENSSIHID AVIDPLSPTG QKLAPLLRIL WKQIQPSMRI 1080 VLNPISSLVD LPLKNFYRFV LPSMDDFSNT DYSVHGPKAF FANMPLSKTL TMNIDVPEPW 1140 LVEPVVAIHD LDNILLENLG DVRTLQAVFE LEALLLTGHC MEKDRDPPRG LQFILGTKQR 1200 PHMVDTLVMA NLGYWQMKVS PGVWYLQLAP GRSADLYELP PKLIAIDSLR GKLMHIEVQK 1260 KKGKEREELL NAADDYHFQE NMDNKGWNNN ILKWASSLIS GDTSSKNKAD KITDRKDGRH 1320 GETINIFSVA SGHLYERFLK IMILSVLKKT QRPVKFWFIK NYLSPQFKDV IPHMAQEYGF 1380 EYELITYKWP TWLHKQKEKQ RIIWAYKILF LDVIFPLSLR KVIFVDADQI VRADMGELYD 1440 MNLKGRPLAY TPFCDNNKDM DGYRFWKQGF WKDHLRGRPY HISALYVVDL AKFRQTAAGD 1500 TLRVFYEQLS KDPNSLSNLD QDLPNYAQHT VPIFSLPQEW LWCESWCGNA TKARAKTIDL 1560 CNNPMTKEPK LQGARRIVPE WAGLDSEARQ FTARILGDNL EPPEATSPPS ETQNPGDKDT 1620 DQNVKDEL* |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
pfam01501 | Glyco_transf_8 | 0.0004 | 1328 | 1523 | 204 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. |
cd04194 | GT8_A4GalT_like | 1.0e-12 | 1324 | 1540 | 226 | + A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS. |
cd00505 | Glyco_transf_8 | 2.0e-56 | 1324 | 1571 | 257 | + Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+. |
pfam06427 | UDP-g_GGTase | 1.0e-84 | 1006 | 1211 | 212 | + UDP-glucose:Glycoprotein Glucosyltransferase. The N-terminal region of this group of proteins is required for correct folding of the ER UDP-Glc: glucosyltransferase. |
cd06432 | GT8_HUGT1_C_like | 1.0e-173 | 1324 | 1571 | 248 | + The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family. C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity. |
Gene Ontology | |
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GO Term | Description |
GO:0003980 | UDP-glucose:glycoprotein glucosyltransferase activity |
GO:0006486 | protein glycosylation |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAD28382.1 | 0 | 1 | 1618 | 1 | 1619 | putative UDP-glucose:glycoprotein glucosyltransferase [Oryza sativa Japonica Group] |
GenBank | EEC73742.1 | 0 | 1 | 1313 | 1 | 1292 | hypothetical protein OsI_08377 [Oryza sativa Indica Group] |
GenBank | EEE57527.1 | 0 | 1 | 1618 | 1 | 1590 | hypothetical protein OsJ_07839 [Oryza sativa Japonica Group] |
RefSeq | XP_002268972.1 | 0 | 21 | 1628 | 11 | 1611 | PREDICTED: similar to EBS1 (EMS-MUTAGENIZED BRI1 SUPPRESSOR 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Vitis vinifera] |
RefSeq | XP_002454743.1 | 0 | 1 | 1628 | 1 | 1568 | hypothetical protein SORBIDRAFT_04g036540 [Sorghum bicolor] |