| Basic Information | |
|---|---|
| Species | Panicum virgatum |
| Cazyme ID | Pavirv00063217m |
| Family | GH89 |
| Protein Properties | Length: 809 Molecular Weight: 91527.3 Isoelectric Point: 7.3676 |
| Chromosome | Chromosome/Scaffold: 000898 Start: 18746 End: 26552 |
| Description | alpha-N-acetylglucosaminidase family / NAGLU family |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH89 | 101 | 805 | 0 |
| AEILIQGTTGVELVSGLHWYLKYWCGAHISWDKTGGAQLASVPSPGSLPRVKGEGVKIERPVPWNYYQNVVTSSYSFVWWDWKRWEKEIDWMALQGINLP LAFTGQEAIWQKVFKSFNVTDRDLDNFFGGPAFLAWARMGNLHGWGGPLSQNWLDQQLVLQKKILSRMIELGMVPVLPSFSGNVPAVFSKLFPSANITRL GDWNTVDADPRWCCTYLLGPSDALFIEVGQAFIKQQIKEYGDVTNIYNCDTFNENTPPTNEPAYISSLGSAIYEAMSRGNKNAVWLMQGWLFYSDAAFWK EPQMKALLHSVPIGKMIVLDLFADVKPIWKMSSQFYGVPYIWCLLHNFGGNIEMYGILDSVASGPIDAHTSYNSTMIGVGMCMEGIEQNPVVYELTAEMA FHDKKVEVEDWLKTYSHRRYGKANAEIEKAWRYLYRTIYNCTDGIADHNKDYIVEFPDISPSAVSSQLSKRRGMSIRSNHKRFFLSEVSGSLPHPHLWYS TKEAIKALELFLDAGNDFSRSLTYRYDLVDLTRQCLSKLANEVYLDAMRSYQKKDLRRLNTHTRKFLEIIVDIDTLLAADDNFLLGPWLESAKSLAVTEN ERKQYEWNARTQVTMWYDNTETEQSKLHDYANKFWSGLLKSYYLPRASEYFAYLTRSLQENRSFQLEEWRKDWISYSNQWQSGKELYAVKSTGDALAISR SLYRK | |||
| Full Sequence |
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| Protein Sequence Length: 809 Download |
| MGPPLPLPLL LLVLLLALLP SPPAAAAAGG LSAWGALRGA AGSRRASPAE QEAAAAGVLR 60 RLLPSHARSF SFQIDSKGSV CGESSCFRIS NVVDDSGKGG AEILIQGTTG VELVSGLHWY 120 LKYWCGAHIS WDKTGGAQLA SVPSPGSLPR VKGEGVKIER PVPWNYYQNV VTSSYSFVWW 180 DWKRWEKEID WMALQGINLP LAFTGQEAIW QKVFKSFNVT DRDLDNFFGG PAFLAWARMG 240 NLHGWGGPLS QNWLDQQLVL QKKILSRMIE LGMVPVLPSF SGNVPAVFSK LFPSANITRL 300 GDWNTVDADP RWCCTYLLGP SDALFIEVGQ AFIKQQIKEY GDVTNIYNCD TFNENTPPTN 360 EPAYISSLGS AIYEAMSRGN KNAVWLMQGW LFYSDAAFWK EPQMKALLHS VPIGKMIVLD 420 LFADVKPIWK MSSQFYGVPY IWCLLHNFGG NIEMYGILDS VASGPIDAHT SYNSTMIGVG 480 MCMEGIEQNP VVYELTAEMA FHDKKVEVED WLKTYSHRRY GKANAEIEKA WRYLYRTIYN 540 CTDGIADHNK DYIVEFPDIS PSAVSSQLSK RRGMSIRSNH KRFFLSEVSG SLPHPHLWYS 600 TKEAIKALEL FLDAGNDFSR SLTYRYDLVD LTRQCLSKLA NEVYLDAMRS YQKKDLRRLN 660 THTRKFLEII VDIDTLLAAD DNFLLGPWLE SAKSLAVTEN ERKQYEWNAR TQVTMWYDNT 720 ETEQSKLHDY ANKFWSGLLK SYYLPRASEY FAYLTRSLQE NRSFQLEEWR KDWISYSNQW 780 QSGKELYAVK STGDALAISR SLYRKYFS* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam12971 | NAGLU_N | 2.0e-21 | 57 | 151 | 95 | + Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This N-terminal domain has an alpha-beta fold. | ||
| pfam12972 | NAGLU_C | 2.0e-102 | 510 | 806 | 297 | + Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This C-terminal domain has an all alpha helical fold. | ||
| pfam05089 | NAGLU | 0 | 166 | 502 | 337 | + Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This central domain has a tim barrel fold. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI24942.1 | 0 | 11 | 808 | 69 | 868 | unnamed protein product [Vitis vinifera] |
| GenBank | EEC75285.1 | 0 | 46 | 807 | 51 | 811 | hypothetical protein OsI_11626 [Oryza sativa Indica Group] |
| GenBank | EEE59081.1 | 0 | 46 | 808 | 51 | 812 | hypothetical protein OsJ_10898 [Oryza sativa Japonica Group] |
| RefSeq | XP_002314048.1 | 0 | 43 | 807 | 38 | 805 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002465249.1 | 0 | 34 | 808 | 39 | 776 | hypothetical protein SORBIDRAFT_01g034960 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2vcc_A | 0 | 93 | 797 | 206 | 867 | A Chain A, Structure Of Uncharacterized Protein (Lmof2365_1472) From Listeria Monocytogenes Serotype 4b |
| PDB | 2vcb_A | 0 | 93 | 797 | 206 | 867 | A Chain A, Structure Of Uncharacterized Protein (Lmof2365_1472) From Listeria Monocytogenes Serotype 4b |
| PDB | 2vca_A | 0 | 93 | 797 | 206 | 867 | A Chain A, Structure Of Uncharacterized Protein (Lmof2365_1472) From Listeria Monocytogenes Serotype 4b |
| PDB | 2vc9_A | 0 | 93 | 797 | 206 | 867 | A Chain A, Family 89 Glycoside Hydrolase From Clostridium Perfringens In Complex With 2-Acetamido-1,2-Dideoxynojirmycin |
| PDB | 4a4a_A | 0 | 93 | 797 | 229 | 890 | A Chain A, Cpgh89 (E483q, E601q), From Clostridium Perfringens, In Complex With Its Substrate Glcnac-Alpha-1,4-Galactose |
