Basic Information | |
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Species | Panicum virgatum |
Cazyme ID | Pavirv00069200m |
Family | GT47 |
Protein Properties | Length: 419 Molecular Weight: 47277.4 Isoelectric Point: 7.1526 |
Chromosome | Chromosome/Scaffold: 009012 Start: 9485 End: 13080 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 51 | 346 | 0 |
KLKVFVYEMPRKYNQMLLSKDSRCLHHMFAAEIFTHQFLLSSAVRTLDPEEADWFYTPVYTTCDLTPQGFPLPFRAPRIMRSAVKYVATTWPYWNRTEGA DHFFLTPHDFGACFHYQEERAMERGILPLLRRATLVQTFGQRNHVCLQEGSITIPPYANPHKMQAHLINPGTPRSIFVYFRGLFYDMGNDPEGGYYARGA RASVWENFKDNPLFDISTEHPSTYYEDMQRAIFCLCPLGWAPWSPRLVEAVVFGCIPVIIADDIVLPFADAIPWEQISVFVAERDVPRLDSILTSI |
Full Sequence |
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Protein Sequence Length: 419 Download |
MGRERRPWPA AAAAVLLLVA SCVAAAPLQQ HQRARITGDA GGVLDDNPVG KLKVFVYEMP 60 RKYNQMLLSK DSRCLHHMFA AEIFTHQFLL SSAVRTLDPE EADWFYTPVY TTCDLTPQGF 120 PLPFRAPRIM RSAVKYVATT WPYWNRTEGA DHFFLTPHDF GACFHYQEER AMERGILPLL 180 RRATLVQTFG QRNHVCLQEG SITIPPYANP HKMQAHLINP GTPRSIFVYF RGLFYDMGND 240 PEGGYYARGA RASVWENFKD NPLFDISTEH PSTYYEDMQR AIFCLCPLGW APWSPRLVEA 300 VVFGCIPVII ADDIVLPFAD AIPWEQISVF VAERDVPRLD SILTSIPLQD ILRKQRLLAG 360 ASVKQALLFH QPARPGDAFD QILNGLARKL PHGKGVFLQP GEKVLDWDAG LESDLKPW* 420 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-81 | 51 | 346 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACG43504.1 | 0 | 30 | 418 | 32 | 420 | secondary cell wall-related glycosyltransferase family 47 [Zea mays] |
GenBank | ACN31576.1 | 0 | 13 | 418 | 6 | 412 | unknown [Zea mays] |
GenBank | ACR34554.1 | 0 | 13 | 418 | 6 | 412 | unknown [Zea mays] |
RefSeq | NP_001045262.1 | 0 | 31 | 418 | 35 | 422 | Os01g0926400 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002459015.1 | 0 | 11 | 418 | 6 | 415 | hypothetical protein SORBIDRAFT_03g044510 [Sorghum bicolor] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |