Basic Information | |
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Species | Phaseolus vulgaris |
Cazyme ID | Phvul.001G050100.1 |
Family | GT47 |
Protein Properties | Length: 480 Molecular Weight: 54977.2 Isoelectric Point: 9.5894 |
Chromosome | Chromosome/Scaffold: 01 Start: 5552206 End: 5560787 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 148 | 431 | 0 |
KIFKVYVYPDGELPIAHDGPCKDIYSIEGRFLHEMEHGAGRFRTNDPNAAHVYFLPFSVTWMVKYLYTPLSYNVTPLKHFVSDYVKVISTRHPFWNRTHG ADHFMLACHDWAPHASQGNHFLYNTSIRVMCNANTSEGFNPRKDVSLPEIHLYGGEVSPKLLSPQSNNITRRYLAFFSGGLHGPIRPILLHHWKNQDGDI RVFEYLPKDLDYYSFMLNSKFCLCPSGHEVASPRIVEAIYAECVPVILSKYYVLPFSDVLQWEAFSVQVDVSDIPRLKDILSAI |
Full Sequence |
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Protein Sequence Length: 480 Download |
MDIPRTYPFP PILTLILLSF VVVVVLRQVQ LLQFTTIAGS KHGHSVPLDR LRMKLSGQNQ 60 LHAIANSGEL RRNKFSHRTA TRKVGKLEQT LAAARASMRN AASESEGERS NLTVATTVHD 120 GGDRNYVPAG AIYRNARLFH RSYLEMEKIF KVYVYPDGEL PIAHDGPCKD IYSIEGRFLH 180 EMEHGAGRFR TNDPNAAHVY FLPFSVTWMV KYLYTPLSYN VTPLKHFVSD YVKVISTRHP 240 FWNRTHGADH FMLACHDWAP HASQGNHFLY NTSIRVMCNA NTSEGFNPRK DVSLPEIHLY 300 GGEVSPKLLS PQSNNITRRY LAFFSGGLHG PIRPILLHHW KNQDGDIRVF EYLPKDLDYY 360 SFMLNSKFCL CPSGHEVASP RIVEAIYAEC VPVILSKYYV LPFSDVLQWE AFSVQVDVSD 420 IPRLKDILSA ISEDEYRKLK EGVKAVRKHF TLNRPSKRFD VFHMILHSIW LRRLNIELR* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-63 | 146 | 431 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI21064.1 | 0 | 33 | 478 | 32 | 477 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_197913.4 | 0 | 87 | 478 | 101 | 479 | catalytic [Arabidopsis thaliana] |
RefSeq | XP_002285237.1 | 0 | 146 | 478 | 1 | 333 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002324871.1 | 0 | 146 | 478 | 1 | 333 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002515489.1 | 0 | 13 | 478 | 17 | 480 | catalytic, putative [Ricinus communis] |