| Basic Information | |
|---|---|
| Species | Phaseolus vulgaris |
| Cazyme ID | Phvul.001G063800.1 |
| Family | GT47 |
| Protein Properties | Length: 443 Molecular Weight: 50844.5 Isoelectric Point: 9.3893 |
| Chromosome | Chromosome/Scaffold: 01 Start: 7952925 End: 7961945 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 68 | 365 | 0 |
| SLKIYVYEPEEINGLNDLLHGRDGKVTEEACLKGQWGTQVKIHKFLLQSKQRTRKKEEADLFFVPSYVKCARMMGGLNDKEINNTYVQVISQMPYFRLSG GRNHIFVFPSGAGAHLFKSWATYINRSIILTPEGDRTDKRDTSAFNTWKDIIIPGNVDDGMTKTGATVVQPLPLPKRKYLANYLGRAQGKAGRLKLIELA KQFPEKLECPDLKFSGPDKLARKEYFEHLRNSKFCLAPRGESSWTLRFYESFFVECVPVIISDQTELPFQNVIDYSQISIKWPSSRVGPELLQYLESI | |||
| Full Sequence |
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| Protein Sequence Length: 443 Download |
| MSASNKWRAM SPHHHQQQPL CTRTHQIGTL LLVTTTFFFT RLLSPCSLST GIVHVSHPQL 60 QWGQSQLSLK IYVYEPEEIN GLNDLLHGRD GKVTEEACLK GQWGTQVKIH KFLLQSKQRT 120 RKKEEADLFF VPSYVKCARM MGGLNDKEIN NTYVQVISQM PYFRLSGGRN HIFVFPSGAG 180 AHLFKSWATY INRSIILTPE GDRTDKRDTS AFNTWKDIII PGNVDDGMTK TGATVVQPLP 240 LPKRKYLANY LGRAQGKAGR LKLIELAKQF PEKLECPDLK FSGPDKLARK EYFEHLRNSK 300 FCLAPRGESS WTLRFYESFF VECVPVIISD QTELPFQNVI DYSQISIKWP SSRVGPELLQ 360 YLESIPDEEI ERIIALGRQV RCWWVYASDS EPCSAMRGIM WELQRKVRQF HHSAETFWLH 420 NGSIVNRNLV QFSKWELPVP LP* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-46 | 69 | 365 | 312 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_564141.1 | 0 | 3 | 442 | 5 | 462 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002265632.1 | 0 | 2 | 442 | 3 | 459 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002300942.1 | 0 | 8 | 442 | 10 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002307477.1 | 0 | 8 | 442 | 10 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002526175.1 | 0 | 21 | 442 | 21 | 453 | catalytic, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| HO781282 | 307 | 20 | 326 | 0 |
| FE707914 | 279 | 109 | 387 | 0 |
| FE707913 | 274 | 170 | 443 | 0 |
| HO803338 | 220 | 25 | 244 | 0 |
| HO781282 | 47 | 319 | 365 | 5e-18 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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