Basic Information | |
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Species | Phaseolus vulgaris |
Cazyme ID | Phvul.001G107400.1 |
Family | GT47 |
Protein Properties | Length: 504 Molecular Weight: 57529.6 Isoelectric Point: 8.8343 |
Chromosome | Chromosome/Scaffold: 01 Start: 27842425 End: 27845517 |
Description | exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 118 | 437 | 0 |
LRVFMYDLPPEFHFGLLDWKPQENANGVWPDIKAVSPHYPGGLNLQHSIEYWLTMDLLASELPEAEAPSKAKSVMRVRNSSEADVIFVPFFSSLCYNRFS KTGPHEKRSRNKVLQEKLVNYVTAQEEWKRSGGKDHVILAHHPNSMLDARTKLWPGTFILSDFGRYPPNVANVEKDVIAPYKHVVGSYDNDQSSFDSRPI LLYFQGAIYRKDGGHVRHELYYLLKSEKDVHFSFGSVQKGGVKKATEGMRSSKFCLNIAGDTPSSNRLFDAIASHCVPVIISDEIELPYEDVLDYSEFCI FVRTRDALKKRYLINFMRSI |
Full Sequence |
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Protein Sequence Length: 504 Download |
MVERTVPGSA IKVVSKKTLC FFFAMTTLLF MLSWLFVLRS TRPDATSNSS LFSSSNDAYS 60 DPVQQKNEEV ETSFGNRAIL GDSIQAAATT TATHDGAQQQ LQQYVPEEQD VKCKPSMLRV 120 FMYDLPPEFH FGLLDWKPQE NANGVWPDIK AVSPHYPGGL NLQHSIEYWL TMDLLASELP 180 EAEAPSKAKS VMRVRNSSEA DVIFVPFFSS LCYNRFSKTG PHEKRSRNKV LQEKLVNYVT 240 AQEEWKRSGG KDHVILAHHP NSMLDARTKL WPGTFILSDF GRYPPNVANV EKDVIAPYKH 300 VVGSYDNDQS SFDSRPILLY FQGAIYRKDG GHVRHELYYL LKSEKDVHFS FGSVQKGGVK 360 KATEGMRSSK FCLNIAGDTP SSNRLFDAIA SHCVPVIISD EIELPYEDVL DYSEFCIFVR 420 TRDALKKRYL INFMRSIGEE EWTKMWNRLK EVESFFEFQF PSKEGDAVQM IWQAVKRKVP 480 FMKLKTNRSR RFFRSIPAAA KYK* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-53 | 118 | 437 | 335 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX33321.1 | 0 | 69 | 494 | 72 | 490 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
RefSeq | NP_190126.1 | 0 | 1 | 501 | 3 | 462 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002319201.1 | 0 | 9 | 492 | 10 | 449 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002325457.1 | 0 | 117 | 494 | 72 | 444 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530948.1 | 0 | 73 | 495 | 66 | 482 | catalytic, putative [Ricinus communis] |