Basic Information | |
---|---|
Species | Phaseolus vulgaris |
Cazyme ID | Phvul.001G112000.1 |
Family | GT47 |
Protein Properties | Length: 416 Molecular Weight: 47814.2 Isoelectric Point: 8.7278 |
Chromosome | Chromosome/Scaffold: 01 Start: 30840098 End: 30847961 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 163 | 379 | 0 |
LLPILTKSHFITIEPTEADIFFLPFSIARLRHDRRVGVGGIQDFIRDYIQNISHKYPYWNRTGGADHFYVACHSIGRSAMDKAPDVKYNAIQVVCSSSYF LTGYIAHKDTCLPQIWPRKGNPPNLDSSKRKKLAFFAGGVNSSVRVKLVETWKNDSEIFVHHGRLNTPYADELLGNKFFLHVKGFELNTTHIGDSLYYGC IPVIIANYYGLPFADVR |
Full Sequence |
---|
Protein Sequence Length: 416 Download |
MPWFVLPSST TALNAVLQAL SRTSSSSPTT LALFTSLFIL FYIYSTSNLF SHNNHHSTSL 60 FKPPSPFSTT PSISTTPHFD PIFHNNDYES TKSQSFQLGY GLRPQSQRGL PLPQQFSPKG 120 KFENNNDVFH DREIFLEDYI EMNRSFKIYV YPHREDDLFA NVLLPILTKS HFITIEPTEA 180 DIFFLPFSIA RLRHDRRVGV GGIQDFIRDY IQNISHKYPY WNRTGGADHF YVACHSIGRS 240 AMDKAPDVKY NAIQVVCSSS YFLTGYIAHK DTCLPQIWPR KGNPPNLDSS KRKKLAFFAG 300 GVNSSVRVKL VETWKNDSEI FVHHGRLNTP YADELLGNKF FLHVKGFELN TTHIGDSLYY 360 GCIPVIIANY YGLPFADVRK HFQWHSPPQD FDPFYMVMYE LWLRRSSIKI WSENS* 420 |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-49 | 142 | 378 | 271 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABD28410.1 | 0 | 28 | 410 | 27 | 481 | Exostosin-like [Medicago truncatula] |
EMBL | CBI39073.1 | 0 | 104 | 410 | 84 | 445 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002265438.1 | 0 | 104 | 410 | 84 | 443 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325425.1 | 0 | 142 | 410 | 1 | 322 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002525728.1 | 0 | 142 | 410 | 1 | 326 | catalytic, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
---|---|---|---|---|
Hit | Length | Start | End | EValue |
JK517670 | 278 | 126 | 386 | 0 |
ES827236 | 284 | 167 | 410 | 0 |
AW570006 | 184 | 173 | 356 | 0 |
DT765011 | 253 | 197 | 409 | 0 |
GR173540 | 212 | 167 | 378 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
---|