Basic Information | |
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Species | Phaseolus vulgaris |
Cazyme ID | Phvul.002G145100.1 |
Family | GT47 |
Protein Properties | Length: 414 Molecular Weight: 47870.5 Isoelectric Point: 8.6587 |
Chromosome | Chromosome/Scaffold: 02 Start: 28190775 End: 28194885 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 89 | 366 | 0 |
EKKFKVYIYPDGDPNTFYQTPRKLTGKYSSEGYFFQNIRESRFRTENPDQAHLFFIPISCHKMRGKGTSYENMTIIVQNYVESLISKYPYWNRTLGADHF FVTCHDVGVRATEGLEFLVKNSIRAVCSPSYDVGFIPHKDVALPQVLQPFALPAGGNDVENRTTLGFWAGHRNSKIRVILARVWENDTELDISNNRISRA TGHLVYQKRFYRSKFCICPGGSQVNSARIADSIHYGCIPVILSNYYDLPFNDIIDWNKFSVVLKEKDVYQLKQILKSI |
Full Sequence |
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Protein Sequence Length: 414 Download |
MTTGKQQSWF FSLRGSLLFL AILTLLSFTY LSLRYSTPPP QVSKLSLTKL GDVPETGREE 60 EQGGGEGEEE YSDTYHSPRV FKLNYEEMEK KFKVYIYPDG DPNTFYQTPR KLTGKYSSEG 120 YFFQNIRESR FRTENPDQAH LFFIPISCHK MRGKGTSYEN MTIIVQNYVE SLISKYPYWN 180 RTLGADHFFV TCHDVGVRAT EGLEFLVKNS IRAVCSPSYD VGFIPHKDVA LPQVLQPFAL 240 PAGGNDVENR TTLGFWAGHR NSKIRVILAR VWENDTELDI SNNRISRATG HLVYQKRFYR 300 SKFCICPGGS QVNSARIADS IHYGCIPVIL SNYYDLPFND IIDWNKFSVV LKEKDVYQLK 360 QILKSISDAE FVALHYNLVK VQKHFQWNSP PIRFDAFHMV MYDLWLRHHT IKY* 420 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-61 | 88 | 366 | 298 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACU18220.1 | 0 | 1 | 413 | 1 | 409 | unknown [Glycine max] |
RefSeq | NP_195517.1 | 0 | 3 | 413 | 12 | 425 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002266299.1 | 0 | 8 | 413 | 14 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002307304.1 | 0 | 12 | 413 | 3 | 406 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002522880.1 | 0 | 64 | 413 | 57 | 406 | catalytic, putative [Ricinus communis] |