Basic Information | |
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Species | Phaseolus vulgaris |
Cazyme ID | Phvul.002G174100.1 |
Family | GT47 |
Protein Properties | Length: 428 Molecular Weight: 50042.5 Isoelectric Point: 9.2642 |
Chromosome | Chromosome/Scaffold: 02 Start: 32400343 End: 32403008 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 51 | 352 | 0 |
SLRVFMYDLPRRFNVGMIDRRNTSETPVTVEDWPRWPENWGLKKQHSVEYWMMGSLIHGVEGREVVRVSDPELANAFFVPFFSSLSFNTHGHTMKDPATE IDRQLQVDLMELLKKSKYWQRSGGRDHVFPVTHPNAFRFLRDQLNDSIQVVVDFGRYPRHMSNLNKDVVSPYVHVVDSLTVDEPQDPYESRSTLLFFRGR TYRKDEGIVRVKLAKILSGYDDVHYERSVATEENIKLSSKGMRSSKFCLHPAGDTPSSCRLFDAIVSHCVPVIVSDQIELPFEDEIEYSQFSIFFSFKEA LQ |
Full Sequence |
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Protein Sequence Length: 428 Download |
MYGKVLLTFI FVLLLLLSYT IFIGNLDIRS YFFPHFKLSA VVPAACALDP SLRVFMYDLP 60 RRFNVGMIDR RNTSETPVTV EDWPRWPENW GLKKQHSVEY WMMGSLIHGV EGREVVRVSD 120 PELANAFFVP FFSSLSFNTH GHTMKDPATE IDRQLQVDLM ELLKKSKYWQ RSGGRDHVFP 180 VTHPNAFRFL RDQLNDSIQV VVDFGRYPRH MSNLNKDVVS PYVHVVDSLT VDEPQDPYES 240 RSTLLFFRGR TYRKDEGIVR VKLAKILSGY DDVHYERSVA TEENIKLSSK GMRSSKFCLH 300 PAGDTPSSCR LFDAIVSHCV PVIVSDQIEL PFEDEIEYSQ FSIFFSFKEA LQPGYMVDQL 360 RKFPKQKWTE MWKQLKNISQ HYEFQYPPKR EDAVSMLWRQ VKHKIPGVSL SVHRSRRLKV 420 PDWWQRK* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-66 | 50 | 352 | 311 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAC18793.1 | 0 | 1 | 405 | 1 | 440 | End is cut off [Arabidopsis thaliana] |
RefSeq | NP_176908.2 | 0 | 1 | 424 | 1 | 429 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002272591.1 | 0 | 27 | 427 | 27 | 429 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002311068.1 | 0 | 52 | 424 | 2 | 380 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002512333.1 | 0 | 1 | 427 | 1 | 434 | catalytic, putative [Ricinus communis] |