Basic Information | |
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Species | Phaseolus vulgaris |
Cazyme ID | Phvul.002G310300.1 |
Family | GT47 |
Protein Properties | Length: 649 Molecular Weight: 74881.2 Isoelectric Point: 10.0815 |
Chromosome | Chromosome/Scaffold: 02 Start: 47186458 End: 47190061 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 317 | 599 | 0 |
RMLKVYIYKDGDKPIFHQPILKGLYASEGWFMKLMEENKHFVVKDPSKAHLFYLPFSARMLEHSLYVRNSHNRTNLRQFLKDYTDKISAKYRHFNRTGGA DHFLVACHDWAPYETRHHMEYCIKALCNADVTQGFKIGRDVSLPEAYVRSVRDPQRDLGGKPPHQRPILAFYAGNMHGYLRPILLKHWKDKDPDMKIYGP MPHGVASKMNYIHHMKNSKYCICPKGYEVNSPRVVEAIFYECVPVIISDNFVPPFFEVLNWDAFSIILAEKDIPNLKQILLSV |
Full Sequence |
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Protein Sequence Length: 649 Download |
MGHRRLLFLL GVLAVNYLLF QSILIPYGSG NAPWSSVPQK YDKVRFPSLH STPKYFTVWS 60 PPMGSVSGFS NSSAFIATVE KMPNPIVQFE VGDGKKMGRH NDENGDLVSE RNLSNDDVFE 120 HGTDKNDARS LSEKKDVGRK GDGLDLESVE SKNFYAILGK GSDVNFSGKQ FSKTKRRASR 180 LVNDNNVDSR EYDGVRVHTS HSSTSSANVT SLENSAQKVV FSASNNSTAM ITPRRKMRCM 240 MPPKTRTLIQ EMNHILVRRR ASARAMRPRW SSKRDLEILA ARLEIEHAPT VTEDKELYAP 300 LFRNISMFKR SYELMERMLK VYIYKDGDKP IFHQPILKGL YASEGWFMKL MEENKHFVVK 360 DPSKAHLFYL PFSARMLEHS LYVRNSHNRT NLRQFLKDYT DKISAKYRHF NRTGGADHFL 420 VACHDWAPYE TRHHMEYCIK ALCNADVTQG FKIGRDVSLP EAYVRSVRDP QRDLGGKPPH 480 QRPILAFYAG NMHGYLRPIL LKHWKDKDPD MKIYGPMPHG VASKMNYIHH MKNSKYCICP 540 KGYEVNSPRV VEAIFYECVP VIISDNFVPP FFEVLNWDAF SIILAEKDIP NLKQILLSVS 600 QEKYLKLQLG VRKAQKHFFW HVKPLKYDLF HMTLHSIWYN RVFQIKLR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-62 | 319 | 599 | 303 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN76867.1 | 0 | 4 | 644 | 725 | 1390 | hypothetical protein [Vitis vinifera] |
EMBL | CAN76867.1 | 0 | 4 | 646 | 16 | 711 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_197468.1 | 0 | 237 | 648 | 199 | 600 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002283936.1 | 0 | 241 | 648 | 1 | 410 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002514248.1 | 0 | 26 | 648 | 38 | 676 | catalytic, putative [Ricinus communis] |