Basic Information | |
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Species | Phaseolus vulgaris |
Cazyme ID | Phvul.003G104800.1 |
Family | GT47 |
Protein Properties | Length: 438 Molecular Weight: 50044.4 Isoelectric Point: 7.6008 |
Chromosome | Chromosome/Scaffold: 03 Start: 25980705 End: 25983403 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 28 | 378 | 0 |
CENRWIHIRRLPSRFNLDLLANCSEYPLLEDLCPFLGNHGLGQKTHNRSHSWYRTDSSMLELIFHRRMLEYPCLTPDPFLAKAIYLPYYAGLDARRYLYG PESNFSALHGLHLFHFLQQDNPQIWARHMAHDHFLVMARPAWDFSQPLTNDPRIWGTSFLELSQFFNLTALTLEARAWPWQEHAVPYPTSFHPPSLGLLE SWLTRVRRSKRSILALFAGGGGGGGGGSSTPNVRRSIHSECENATSDPSYEKLCEIVDCSNGVCEHDPIRFMRPMLQASFCLQPPGDTPTRRSTFDAILA GCIPVFFEELSAKSQYGWHLPENEYEDFSVLIPKEEVVFRGLRILNVLQRI |
Full Sequence |
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Protein Sequence Length: 438 Download |
MGVLKGSVWG LLMIVWVWKL AAGEEEKCEN RWIHIRRLPS RFNLDLLANC SEYPLLEDLC 60 PFLGNHGLGQ KTHNRSHSWY RTDSSMLELI FHRRMLEYPC LTPDPFLAKA IYLPYYAGLD 120 ARRYLYGPES NFSALHGLHL FHFLQQDNPQ IWARHMAHDH FLVMARPAWD FSQPLTNDPR 180 IWGTSFLELS QFFNLTALTL EARAWPWQEH AVPYPTSFHP PSLGLLESWL TRVRRSKRSI 240 LALFAGGGGG GGGGSSTPNV RRSIHSECEN ATSDPSYEKL CEIVDCSNGV CEHDPIRFMR 300 PMLQASFCLQ PPGDTPTRRS TFDAILAGCI PVFFEELSAK SQYGWHLPEN EYEDFSVLIP 360 KEEVVFRGLR ILNVLQRIPR AKVRSLRQRV LTLIPNVLYR KHDSSPGLED KKDAFDLAID 420 GTLDKIRSRV EKLDSVI* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-47 | 27 | 378 | 360 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_193989.1 | 0 | 22 | 430 | 31 | 435 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002267390.1 | 0 | 27 | 433 | 32 | 441 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002304426.1 | 0 | 22 | 430 | 23 | 429 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002329867.1 | 0 | 25 | 434 | 30 | 436 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002529790.1 | 0 | 28 | 431 | 37 | 450 | catalytic, putative [Ricinus communis] |