Basic Information | |
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Species | Phaseolus vulgaris |
Cazyme ID | Phvul.003G169600.1 |
Family | GT47 |
Protein Properties | Length: 468 Molecular Weight: 54071.4 Isoelectric Point: 9.5828 |
Chromosome | Chromosome/Scaffold: 03 Start: 38017499 End: 38020859 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 134 | 418 | 0 |
KRFRVWTYREGETPLVHLGPTSSIYGIEGHVIAEIDNIRSPFSARHPDEAHVFMLPVSVSQIVRYLYNPLTTYSRDELMRVTIDYTNIIATRYPYWNRST GADHFLASCHDWAPDISREKSGKELFKNMIRVLCNANTSEGFKPEKDVSMPEMNLQGYKLSSPIPGDDPDNRSILAFFAGGAHGRIREILLEHWKDKDEE VQVHEYLPKGMDYHGLMGQSRFCLCPSGYEVASPRVVESINAGCVPVIVSDYYQLPFSDVLDWSKFSLHIPSKRITEIKTILKSV |
Full Sequence |
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Protein Sequence Length: 468 Download |
MPTFNSWLLF SVTLFTVLIL LAFFAHQRND VAFLLPAINV LPSEEHLKTL DASKEQHRTL 60 PFTPTIVKTR PLHIKKKSNS LMRIEEDLAE ARAAIRRAIE RRNFTSEKEE IFVPRGNVYR 120 NAYAFHQSHI EMLKRFRVWT YREGETPLVH LGPTSSIYGI EGHVIAEIDN IRSPFSARHP 180 DEAHVFMLPV SVSQIVRYLY NPLTTYSRDE LMRVTIDYTN IIATRYPYWN RSTGADHFLA 240 SCHDWAPDIS REKSGKELFK NMIRVLCNAN TSEGFKPEKD VSMPEMNLQG YKLSSPIPGD 300 DPDNRSILAF FAGGAHGRIR EILLEHWKDK DEEVQVHEYL PKGMDYHGLM GQSRFCLCPS 360 GYEVASPRVV ESINAGCVPV IVSDYYQLPF SDVLDWSKFS LHIPSKRITE IKTILKSVPR 420 AKYLKLHKRV MKVQRHFVLN RPAKSFDVFH MILHSVWLRR LNIRLPN* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-59 | 132 | 418 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABP03863.1 | 0 | 127 | 466 | 40 | 379 | Exostosin-like [Medicago truncatula] |
EMBL | CBI21065.1 | 0 | 72 | 466 | 7 | 401 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_197526.4 | 0 | 75 | 466 | 18 | 408 | catalytic [Arabidopsis thaliana] |
Swiss-Prot | Q3E9A4 | 0 | 75 | 466 | 76 | 466 | GLYT5_ARATH RecName: Full=Probable glycosyltransferase At5g20260 |
RefSeq | XP_002531945.1 | 0 | 61 | 466 | 58 | 451 | catalytic, putative [Ricinus communis] |