Basic Information | |
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Species | Phaseolus vulgaris |
Cazyme ID | Phvul.003G169800.1 |
Family | GT47 |
Protein Properties | Length: 469 Molecular Weight: 54325.8 Isoelectric Point: 10.0671 |
Chromosome | Chromosome/Scaffold: 03 Start: 38042285 End: 38044373 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 132 | 418 | 0 |
KRLKVWVYKEGEQPLVHDGPVNNKYSIEGQFIDEMDIANKSPFKAHNPEQAHLFLLPFTVSKVIRYVYKPRRSRSDYDPPRLQRLVEDYINVVANRYPYW NRSKGADHFLVSCHDWGPKVSYANPQLFKYFIRVLCNANTSEGFEPNRDVSIPEVFLPVGKLGPPKMGQHLNNRPILAFFAGGAHGKIRKTLLKQWKDKD REVEVHEYLGKGEDYTKLMGLSKFCLCPSGHEVASPRVVEAIYAGCVPVIISHNYSLPFSDVLDWSEFSIQIAVERIAEIKIILQNV |
Full Sequence |
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Protein Sequence Length: 469 Download |
MKVFKSSLSS LVFLVFFLNF FLVCFTPSHD SQVIHVHSES PFTLSSIRGN TSPQEIHYNN 60 TDLRWIKFGH GMKKNVTSLE RLEEGLARSR AFIQKAIRYK NHTSLVKESF VPKTAIYRNP 120 HAFHQSHVEM MKRLKVWVYK EGEQPLVHDG PVNNKYSIEG QFIDEMDIAN KSPFKAHNPE 180 QAHLFLLPFT VSKVIRYVYK PRRSRSDYDP PRLQRLVEDY INVVANRYPY WNRSKGADHF 240 LVSCHDWGPK VSYANPQLFK YFIRVLCNAN TSEGFEPNRD VSIPEVFLPV GKLGPPKMGQ 300 HLNNRPILAF FAGGAHGKIR KTLLKQWKDK DREVEVHEYL GKGEDYTKLM GLSKFCLCPS 360 GHEVASPRVV EAIYAGCVPV IISHNYSLPF SDVLDWSEFS IQIAVERIAE IKIILQNVSK 420 DKYRKLYYNV RRVGRHFVIN RPAKPFDLIH MILHSLWLRR LNFQLPPS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-66 | 130 | 418 | 307 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABP03872.1 | 0 | 1 | 465 | 20 | 465 | Exostosin-like [Medicago truncatula] |
GenBank | ABP03873.1 | 0 | 67 | 465 | 225 | 613 | Exostosin-like [Medicago truncatula] |
EMBL | CAN76361.1 | 0 | 77 | 466 | 64 | 458 | hypothetical protein [Vitis vinifera] |
EMBL | CBI25537.1 | 0 | 77 | 466 | 86 | 476 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002263848.1 | 0 | 77 | 466 | 5 | 395 | PREDICTED: hypothetical protein [Vitis vinifera] |