Basic Information | |
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Species | Phaseolus vulgaris |
Cazyme ID | Phvul.003G169900.1 |
Family | GT47 |
Protein Properties | Length: 469 Molecular Weight: 53985 Isoelectric Point: 9.6571 |
Chromosome | Chromosome/Scaffold: 03 Start: 38045483 End: 38047321 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 131 | 417 | 0 |
KRFKVWVYEEGEQPLVHYGPVNDIYAIEGQFIDELDNSKRSPFKARNPDVAHAFFIPFSVVNVVHYVYKPYMSQNDYRRDRLQRLVEDYIGVVAEKYPYW NRSNGADHFLLSCHDWAPDISHANPKLFKNFIKALCNANTSEGFQPKRDVSIPEVYLPVGKLGPPNLGQHPMNRSILAFFSGGAHGDIRKLLLKHWKDKD SQVQVHEYLQRGQNYTELMGLSKFCLCPSGYEVASPRVVEAIHVGCVPVIISEDYALPFSDVLNWNQFSVQIPVYNIPKIKTILQNV |
Full Sequence |
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Protein Sequence Length: 469 Download |
MVPSRCSPPS MLFPLFLPIL LFIFITHLKG NHLSVDFPYF SLSTIKDITT QVQPHVQSLA 60 NSAYRSLDHS IKKRTSFDVV EEGLAKARAS IQEAIRSGNH NSSGNQEDFI PKGSIYRNPY 120 AFHQSHKEMV KRFKVWVYEE GEQPLVHYGP VNDIYAIEGQ FIDELDNSKR SPFKARNPDV 180 AHAFFIPFSV VNVVHYVYKP YMSQNDYRRD RLQRLVEDYI GVVAEKYPYW NRSNGADHFL 240 LSCHDWAPDI SHANPKLFKN FIKALCNANT SEGFQPKRDV SIPEVYLPVG KLGPPNLGQH 300 PMNRSILAFF SGGAHGDIRK LLLKHWKDKD SQVQVHEYLQ RGQNYTELMG LSKFCLCPSG 360 YEVASPRVVE AIHVGCVPVI ISEDYALPFS DVLNWNQFSV QIPVYNIPKI KTILQNVSEG 420 KYMKLHRNVR RVRRHFVVNR PAKPFDLMHM IFHSIWLRRL NFRLMASQ* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 6.0e-66 | 129 | 417 | 307 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABP03872.1 | 0 | 72 | 468 | 74 | 469 | Exostosin-like [Medicago truncatula] |
GenBank | ABP03873.1 | 0 | 26 | 468 | 178 | 617 | Exostosin-like [Medicago truncatula] |
EMBL | CBI21065.1 | 0 | 71 | 464 | 9 | 400 | unnamed protein product [Vitis vinifera] |
EMBL | CBI25537.1 | 0 | 57 | 464 | 60 | 475 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002263848.1 | 0 | 71 | 464 | 1 | 394 | PREDICTED: hypothetical protein [Vitis vinifera] |