Basic Information | |
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Species | Phaseolus vulgaris |
Cazyme ID | Phvul.003G190200.1 |
Family | GT47 |
Protein Properties | Length: 491 Molecular Weight: 56431.1 Isoelectric Point: 10.0062 |
Chromosome | Chromosome/Scaffold: 03 Start: 40211781 End: 40213854 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 109 | 426 | 0 |
LRVFMYDLPPEFHFGLLDWKGSANQTWPIVNNPKHVPPYPGGLNLQHSVEYWLTLDLLSSNIANVFRPCSAIRVQNASQADVVFVPFFSSLSYNQHSKIH GKEKVSVNKMLQGRLVQFLMEREEWKRSGGTDHVIVAHHPNSMVHARRKLGSSIFVLADFGRYHSKIANIQKDIIAPYRHLVNTIPRAESASYKERSTLL YFQGAIYRKSGGAVRREIYHLLKDEKDVHFTFGSIRRNGIKQASQGMALSKFCLNIAGDTPSSNRLFDAIVSHCVPVIISDEIELPFEDVLDYSEFSLFV RASDAVRKGYLLNLLRSI |
Full Sequence |
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Protein Sequence Length: 491 Download |
MSDNNLVPPR FFMFCFMIIA MFLLVLYSSF LLHFSSHSFI PRSVLDLVLA NNTSLDFKPS 60 FKREHITPPL HSQVSKVQPQ RCQLFNSSQK STSPKQLRKM ACDTTLALLR VFMYDLPPEF 120 HFGLLDWKGS ANQTWPIVNN PKHVPPYPGG LNLQHSVEYW LTLDLLSSNI ANVFRPCSAI 180 RVQNASQADV VFVPFFSSLS YNQHSKIHGK EKVSVNKMLQ GRLVQFLMER EEWKRSGGTD 240 HVIVAHHPNS MVHARRKLGS SIFVLADFGR YHSKIANIQK DIIAPYRHLV NTIPRAESAS 300 YKERSTLLYF QGAIYRKSGG AVRREIYHLL KDEKDVHFTF GSIRRNGIKQ ASQGMALSKF 360 CLNIAGDTPS SNRLFDAIVS HCVPVIISDE IELPFEDVLD YSEFSLFVRA SDAVRKGYLL 420 NLLRSIKPEK WTKMCERLKD ITQHFEYQYP SQPRDAVNMI WEQVAHKISS LQLNLHRKNR 480 YHTRDLSFLL * |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-57 | 109 | 426 | 327 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_565089.1 | 0 | 102 | 486 | 68 | 454 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002284930.1 | 0 | 33 | 481 | 32 | 445 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
RefSeq | XP_002284932.1 | 0 | 82 | 481 | 7 | 406 | PREDICTED: hypothetical protein isoform 2 [Vitis vinifera] |
RefSeq | XP_002320639.1 | 0 | 109 | 481 | 3 | 372 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002514760.1 | 0 | 35 | 481 | 34 | 484 | catalytic, putative [Ricinus communis] |