y
Basic Information | |
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Species | Phaseolus vulgaris |
Cazyme ID | Phvul.005G076500.2 |
Family | GT20 |
Protein Properties | Length: 944 Molecular Weight: 106382 Isoelectric Point: 7.1168 |
Chromosome | Chromosome/Scaffold: 05 Start: 15242188 End: 15253050 |
Description | trehalose-6-phosphate synthase |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 104 | 571 | 0 |
KQRLLVVANRLPVSAIRKGEDSWSLEISAGGLVSALLGVKALEARWIGWAGVNVPDEIGQKALTKALAEKRCIPVFLDEEIVHQYYNGYCNNILWPLFHY LGLPQEDRLATTRSFQSQFEAYQKANQMFADVVNKHYEEGDVVWCHDYHLMFLPQCLKNYNSKMKVGWFLHTPFPSSEIHRTLPSRSELLHAVLAADLVG FHTYDYARHFVSACTRILGLEGTPEGVENQGKLTRVAAFPIGIDSERFIRALDLPQVKVHIEDLQERFKGRKVMLGVDRLDMIKGIPQKILAFEKFLEEN PDWRDKVVLLQIAVPTRTDVPEYQKLTSQVHEIVGRINGRFGTLATVPIHHLDCSLDFQKLCALYAVTDVALVTSLRDGMNLVSYEFVACQDKKKGVLIL SEFAGAAQSLGAGAILVNPWNITEVAAAIAKALNMKSEEREKRHKHNFKHVTTHTAQEWAETFVSELN |
Full Sequence |
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Protein Sequence Length: 944 Download |
MVGFQSEHKE GNKYNGNSNN IPDRIQRLMR RRDLLKISKA SLSNEGPDSN NNNNNNINNN 60 VITEYFEHDP RLREDNNSAA SNERLLEGVA AALRGEVEDG RPFKQRLLVV ANRLPVSAIR 120 KGEDSWSLEI SAGGLVSALL GVKALEARWI GWAGVNVPDE IGQKALTKAL AEKRCIPVFL 180 DEEIVHQYYN GYCNNILWPL FHYLGLPQED RLATTRSFQS QFEAYQKANQ MFADVVNKHY 240 EEGDVVWCHD YHLMFLPQCL KNYNSKMKVG WFLHTPFPSS EIHRTLPSRS ELLHAVLAAD 300 LVGFHTYDYA RHFVSACTRI LGLEGTPEGV ENQGKLTRVA AFPIGIDSER FIRALDLPQV 360 KVHIEDLQER FKGRKVMLGV DRLDMIKGIP QKILAFEKFL EENPDWRDKV VLLQIAVPTR 420 TDVPEYQKLT SQVHEIVGRI NGRFGTLATV PIHHLDCSLD FQKLCALYAV TDVALVTSLR 480 DGMNLVSYEF VACQDKKKGV LILSEFAGAA QSLGAGAILV NPWNITEVAA AIAKALNMKS 540 EEREKRHKHN FKHVTTHTAQ EWAETFVSEL NDTIDEAQLR TKQAPPRLPT ETAVERYLQS 600 NNRLLILGFN GTLTVPVERK GDQYQETELT MHPELKQPLA ELCSDPKTTV VVLSGSGRPV 660 LDQNFKEYDI WLAAENGMFL NPSKGEWMTT MPEQLNMEWV DSVKHVFDYF TDRTPRSHFE 720 EREASLVWSY RHSDGEFGKL QARDMLQHLW TGPISNASVE VVQGSRSVEV RAANVTKGAA 780 IDRILGEIVH SKSMTTPIDY VLCIGHFLTK DEDIYSFFEP ELPSIGVGLP RSKVTEGVKF 840 PAERISSLKK IPASKNGAAK SSQNKGQRVM PSSERKTNNH VCRAPRRPAP EKISWNVLDL 900 KKENYFSCAV GRTQTNARYT LGSPDEVVAF LKELVNSSPY SYV* 960 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN03064 | PLN03064 | 0 | 10 | 938 | 941 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN03063 | PLN03063 | 0 | 98 | 934 | 837 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PRK14501 | PRK14501 | 0 | 106 | 828 | 733 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
TIGR02400 | trehalose_OtsA | 0 | 106 | 572 | 469 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming]. This enzyme catalyzes the key, penultimate step in biosynthesis of trehalose, a compatible solute made as an osmoprotectant in some species in all three domains of life. The gene symbol OtsA stands for osmotically regulated trehalose synthesis A. Trehalose helps protect against both osmotic and thermal stresses, and is made from two glucose subunits. This model excludes glucosylglycerol-phosphate synthase, an enzyme of an analogous osmoprotectant system in many cyanobacterial strains. This model does not identify archaeal examples, as they are more divergent than glucosylglycerol-phosphate synthase. Sequences that score in the gray zone between the trusted and noise cutoffs include a number of yeast multidomain proteins in which the N-terminal domain may be functionally equivalent to this family. The gray zone also includes the OtsA of Cornyebacterium glutamicum (and related species), shown to be responsible for synthesis of only trace amounts of trehalose while the majority is synthesized by the TreYZ pathway; the significance of OtsA in this species is unclear (see Wolf, et al., PMID:12890033) [Cellular processes, Adaptations to atypical conditions]. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABO61742.1 | 0 | 11 | 937 | 3 | 919 | trehalose-phosphate synthase 1 [Solanum lycopersicum] |
RefSeq | NP_177979.1 | 0 | 11 | 938 | 3 | 939 | ATTPS1 (TREHALOSE-6-PHOSPHATE SYNTHASE); alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002285632.1 | 0 | 11 | 937 | 3 | 923 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002331300.1 | 0 | 11 | 938 | 3 | 921 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002531237.1 | 0 | 11 | 938 | 3 | 923 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1uqu_B | 0 | 106 | 591 | 3 | 476 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
PDB | 1uqu_A | 0 | 106 | 591 | 3 | 476 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
PDB | 1uqt_B | 0 | 106 | 591 | 3 | 476 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
PDB | 1uqt_A | 0 | 106 | 591 | 3 | 476 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
PDB | 2wtx_D | 0 | 106 | 584 | 3 | 468 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
CX546763 | 313 | 86 | 395 | 0 |
CV711307 | 293 | 104 | 396 | 0 |
DW069910 | 288 | 192 | 479 | 0 |
GO265628 | 300 | 461 | 760 | 0 |
ES813375 | 361 | 467 | 824 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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