| Basic Information | |
|---|---|
| Species | Phaseolus vulgaris |
| Cazyme ID | Phvul.005G131200.1 |
| Family | GH29 |
| Protein Properties | Length: 536 Molecular Weight: 60305.6 Isoelectric Point: 6.5608 |
| Chromosome | Chromosome/Scaffold: 05 Start: 35650568 End: 35653552 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH29 | 64 | 359 | 0 |
| LQWQLRDMSLFFHFGPNTFTDSEWGSGHAHPSVFNPTKLNPSQWIRVAKNCGFSTVILTVKHHDGFCLWPSDYTDYSLRSSNWKNGSGDVVAELSSAAKD AGVGFGIYLSPWDRHETSFGDTLRYNEFYLAQMTELLTRYGEITDVFLDGAKGEGEKDMNYLYTSWNSLIHQLQPGVSIFSDLGPETRWVGNEYGIAGFT CWSLFNKTGFEIGQIDLQYNSEGDPLGPDWIPATCDVSIRPGWFWHASESPMSARSLLEIYYKSVGRNCKLLLNVPPNSSGLISDEDIQVLQEFAE | |||
| Full Sequence |
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| Protein Sequence Length: 536 Download |
| MKLNKSSRSW CKPHNPLIKI STCRLPNFPI QILLLGLCHL LVPASCSRKP PPLPILPLPT 60 ALQLQWQLRD MSLFFHFGPN TFTDSEWGSG HAHPSVFNPT KLNPSQWIRV AKNCGFSTVI 120 LTVKHHDGFC LWPSDYTDYS LRSSNWKNGS GDVVAELSSA AKDAGVGFGI YLSPWDRHET 180 SFGDTLRYNE FYLAQMTELL TRYGEITDVF LDGAKGEGEK DMNYLYTSWN SLIHQLQPGV 240 SIFSDLGPET RWVGNEYGIA GFTCWSLFNK TGFEIGQIDL QYNSEGDPLG PDWIPATCDV 300 SIRPGWFWHA SESPMSARSL LEIYYKSVGR NCKLLLNVPP NSSGLISDED IQVLQEFAEL 360 RRSIFSHNLA INAVINASSI RGGIQDTHFS PYNILKEGIY TYWAPEENQT KWILYINLEE 420 LVSFNVLQLQ EPIHMGQRVI EFHLETLSQD GVWMRVVNGT TIGYQRLLLF PKLKSQYLKL 480 VVDKSRADPL ISYLGIYMDS VTVLRDTPDK KSGASFNGSQ VLQTTTHNSS LSAAM* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01120 | Alpha_L_fucos | 1.0e-30 | 65 | 359 | 316 | + Alpha-L-fucosidase. | ||
| smart00812 | Alpha_L_fucos | 6.0e-31 | 97 | 359 | 285 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| COG3669 | COG3669 | 3.0e-66 | 65 | 497 | 451 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_180377.2 | 0 | 49 | 526 | 28 | 496 | ATFUC1 (alpha-L-fucosidase 1); alpha-L-fucosidase [Arabidopsis thaliana] |
| Swiss-Prot | Q8GW72 | 0 | 49 | 526 | 28 | 496 | FUCO1_ARATH RecName: Full=Alpha-L-fucosidase 1; AltName: Full=Alpha-L-fucoside fucohydrolase; AltName: Full=Alpha-1,3/4-fucosidase; Short=AtFUC1; Flags: Precursor |
| RefSeq | XP_002276131.1 | 0 | 60 | 520 | 51 | 509 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002313533.1 | 0 | 60 | 502 | 15 | 457 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523703.1 | 0 | 60 | 506 | 64 | 511 | alpha-l-fucosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3ues_B | 0 | 59 | 492 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3ues_A | 0 | 59 | 492 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3mo4_B | 0 | 59 | 492 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3mo4_A | 0 | 59 | 492 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3uet_B | 0 | 59 | 492 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis D172aE217A MUTANT COMPLEXED WITH LACTO-N- Fucopentaose Ii |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| CX711036 | 272 | 265 | 536 | 0 |
| FK016895 | 258 | 279 | 536 | 0 |
| CX708016 | 240 | 297 | 536 | 0 |
| DY270181 | 285 | 65 | 349 | 0 |
| DY300194 | 325 | 88 | 410 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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