Basic Information | |
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Species | Phaseolus vulgaris |
Cazyme ID | Phvul.006G201500.1 |
Family | GT47 |
Protein Properties | Length: 416 Molecular Weight: 48674 Isoelectric Point: 9 |
Chromosome | Chromosome/Scaffold: 06 Start: 30591286 End: 30594912 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 91 | 368 | 0 |
EEFKVFVYPDGDPETYFHTPRKLTGKYASEGYFFKNIRESRFVTDDPRRAHLFFLPISCHKMRGRGLTNEDMIDEVKKYVEYVKFKYPYWNRTLGADHFF VTCHDIGVKATKGVPHLMKNSIRVVCSSRYDDDDYIPHKDVTLPQVQLPFFHPPGGNDFKNRNTLAFWAGRSDSRLKDDLTAMWDNDTELDIQNNRIDFR ATGHLVFMERLYKSKFCLCPHGPIGSSRITDSIHFGCVPVIMSNYYDLPFNDVLDWRKFSVILKETDVYLLKDILRSI |
Full Sequence |
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Protein Sequence Length: 416 Download |
MSPSREKSIS VANLPAVRNR PRGPRGSCGS CGSVNLATTA CIVVNVIYML LLFVCSKQLH 60 SPLRKRAFLF DSSVFHFPEE AFRLDYEQME EEFKVFVYPD GDPETYFHTP RKLTGKYASE 120 GYFFKNIRES RFVTDDPRRA HLFFLPISCH KMRGRGLTNE DMIDEVKKYV EYVKFKYPYW 180 NRTLGADHFF VTCHDIGVKA TKGVPHLMKN SIRVVCSSRY DDDDYIPHKD VTLPQVQLPF 240 FHPPGGNDFK NRNTLAFWAG RSDSRLKDDL TAMWDNDTEL DIQNNRIDFR ATGHLVFMER 300 LYKSKFCLCP HGPIGSSRIT DSIHFGCVPV IMSNYYDLPF NDVLDWRKFS VILKETDVYL 360 LKDILRSISE KHFMILNQNL VKIQKHFNWN TPPVRLDAFH MVMYELWRRR HLIRY* 420 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-51 | 93 | 368 | 300 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACU18220.1 | 0 | 74 | 415 | 70 | 409 | unknown [Glycine max] |
RefSeq | XP_002266299.1 | 0 | 72 | 415 | 75 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002268836.1 | 0 | 72 | 415 | 76 | 417 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002307304.1 | 0 | 72 | 415 | 65 | 406 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002522880.1 | 0 | 82 | 415 | 74 | 406 | catalytic, putative [Ricinus communis] |