Basic Information | |
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Species | Phaseolus vulgaris |
Cazyme ID | Phvul.006G215600.1 |
Family | GT24 |
Protein Properties | Length: 1639 Molecular Weight: 185285 Isoelectric Point: 5.9022 |
Chromosome | Chromosome/Scaffold: 06 Start: 31569425 End: 31587325 |
Description | UDP-glucose:glycoprotein glucosyltransferases;transferases, transferring hexosyl groups;transferases, transferring glycosyl groups |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT24 | 1334 | 1581 | 0 |
INIFSIASGHLYERFLKIMILTVLKNTQRPVKFWFIKNYLSPPFKDLIPRMAQEYGFECELITYKWPTWLHKQNEKQRIIWAYKILFLDVIFPLSLEKVI FVDADQIVRTDMGELYDMDIKGKPLAYTPFCDNNKEMDGYRFWRQGFWKDHLRGKPYHISALYVVDLKKFRETAAGDNLRVFYETLSKDPNSLANLDQDL PNYAQHVVPIFSLPQEWLWCESWCGNATKSRAKTIDLCNNPMTKEPKL |
Full Sequence |
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Protein Sequence Length: 1639 Download |
MGLRSESPLL LLILILLLAI ASAHTPTPKN VQTSLRAKWF GTPLLLEAGE LLFKEEPRLF 60 WNFIHAWLHA DDHGDAHSHS ARSCVNEILH HSRPLLREPL ASLFEFSLIL RSASPALVLY 120 RQLAHDSLSS HSYAPITKLD PLHLGVSLQS PGGKCCWVDT GDTLFFDVSE LLLWLQTPLE 180 KVGGSIPGPQ LFDFDHVHFD SSVGSPVAVL YGALGTVCFK EFHDALVGAA KQGKVNYILR 240 PVLPAGCETN FGHCGSVGAS ESINLGGYGV ELAFKNMEYK AMDDSTIKKG VTLEDPRTED 300 LSQEVRGFIF SKILERKPEL TYEIMTFRDY LLSSTVSDTL DVWELKDLGH QTVQRIVRAS 360 DPLQSMQDIN QNFPNIVSSL SRMKLDDSVR DEIMANQRMI PPGKSLMAIN GALVNVEDVD 420 LYLLIDLVHQ DLLLADQFSK LKIPPSIVRK LLSTLPPSES SMFRVDFRTT QVHYLNNLEE 480 DAKYKRWRSN LNEILMPVFP GQLRHIRKNL FHAVFVLDPA TISGLEASLF SKANTLFFVN 540 SFSKRNLSFL ELLLGTLQSI DMIISLYESD FPVRFGVVLY SSKYITQLEN LSAKEDRDKF 600 EEDISDMIIR LFSYIKGHHD TQLAFEFLSN VNKLRTESDD GHLELHHVEG AFVETILPKV 660 KSPPQEILLK LEKESELKEL SQESSMLAFK LGLSKTHCSL LMNGLVIDPT EDALLNALND 720 ETQRIQEQVY FGQIKPHTDV LAKFLSEAGI QRYNPRIISD SKPRFVSLSA FLFGEESILN 780 DIEYLHSPGT MDELKPVTHL LAVDITSRSG LHLLRQGLNY LREGSKDARI GLLFSANWST 840 DSLSVLFVKV FEITSSSYSH KKNVLDFLDQ LCLLYQQKYF PTSAVEVEGT QTFIDKVCEL 900 AEANGLPSEG YRPALLKFSA DEVRRHLNKV GIFLHRLLGS ESGVNAVFTN GRVTYPIDES 960 TFLSADLLLL ESIEFKQRTK HILEIIEEVK WQHVDPDMLT SKFISDIVMA VSSSMAVRER 1020 SSESARFEIL NDQHSAIILH NENSSIHIDA CLDPLSATSQ KLSGILRVLW KYIQPSMRIV 1080 LNPLSSLADL PLKNYYRYVV PSMDDFSIAD SSINGPKAFF ANMPLSKTLT MNLDVPEPWL 1140 VEPVIAVHDL DNILLENLGD TRTLQAVFEL EALVLTGHCS EKDHDPPRGL QLILGTKTTP 1200 HLVDTIVMAN LGYWQMKVSP GVWFLQLAPG RSSELYILKE GADGIQSKQL SKLITISDLR 1260 GKVVHMDVVK KKGRENEKLL VSDDEEDPQE TKKGSGWNSN LLKWASGFIS SNEQPKISET 1320 NAEKVKGGRS GKTINIFSIA SGHLYERFLK IMILTVLKNT QRPVKFWFIK NYLSPPFKDL 1380 IPRMAQEYGF ECELITYKWP TWLHKQNEKQ RIIWAYKILF LDVIFPLSLE KVIFVDADQI 1440 VRTDMGELYD MDIKGKPLAY TPFCDNNKEM DGYRFWRQGF WKDHLRGKPY HISALYVVDL 1500 KKFRETAAGD NLRVFYETLS KDPNSLANLD QDLPNYAQHV VPIFSLPQEW LWCESWCGNA 1560 TKSRAKTIDL CNNPMTKEPK LQGARRIVPE WPDLDLEASK FTAQILGDDL EPFPSPNQSK 1620 DLISEDALKE DLESKAEL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam01501 | Glyco_transf_8 | 1.0e-5 | 1338 | 1533 | 206 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. | ||
cd04194 | GT8_A4GalT_like | 4.0e-16 | 1334 | 1550 | 227 | + A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS. | ||
cd00505 | Glyco_transf_8 | 2.0e-54 | 1334 | 1581 | 257 | + Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+. | ||
pfam06427 | UDP-g_GGTase | 2.0e-77 | 1005 | 1210 | 212 | + UDP-glucose:Glycoprotein Glucosyltransferase. The N-terminal region of this group of proteins is required for correct folding of the ER UDP-Glc: glucosyltransferase. | ||
cd06432 | GT8_HUGT1_C_like | 4.0e-171 | 1334 | 1581 | 248 | + The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family. C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity. |
Gene Ontology | |
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GO Term | Description |
GO:0003980 | UDP-glucose:glycoprotein glucosyltransferase activity |
GO:0006486 | protein glycosylation |
GO:0016757 | transferase activity, transferring glycosyl groups |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAG51883.1 | 0 | 9 | 1638 | 11 | 1674 | AC016162_4 putative UDP-glucose:glycoprotein glucosyltransferase; 101200-91134 [Arabidopsis thaliana] |
GenBank | EEE57527.1 | 0 | 77 | 1611 | 51 | 1573 | hypothetical protein OsJ_07839 [Oryza sativa Japonica Group] |
RefSeq | NP_177278.3 | 0 | 9 | 1638 | 11 | 1613 | EBS1 (EMS-mutagenized bri1 suppressor 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002268972.1 | 0 | 14 | 1638 | 11 | 1611 | PREDICTED: similar to EBS1 (EMS-MUTAGENIZED BRI1 SUPPRESSOR 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Vitis vinifera] |
RefSeq | XP_002529534.1 | 0 | 1 | 1531 | 1 | 1499 | UDP-glucose glycoprotein:glucosyltransferase, putative [Ricinus communis] |