y
Basic Information | |
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Species | Phaseolus vulgaris |
Cazyme ID | Phvul.007G066200.1 |
Family | AA3 |
Protein Properties | Length: 581 Molecular Weight: 64067.3 Isoelectric Point: 9.0442 |
Chromosome | Chromosome/Scaffold: 07 Start: 5884696 End: 5887976 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 39 | 569 | 0 |
SAPPILSYDYIVIGGGTSGCPLAATLSQGARVLVLERGGSPYTNPERINIKNFVNSLADISPSSFSQPFISTDGVLNARARVLGGGSVLNAGFYSRASSE YIRTSGWNESLAEESYKWVERKVVFEPPMLQWQSAVRDGLLEVGVLPYNDFTYDHLNGTKIGGTIFDNKGNRHTAADLLEYADPKRISVYLHATVQKILF KYNTGKRRPEAYGVIFRDALGVMHRAYLNTNGKNEIILSAGAIGSPQLLMLSGIGPARHLQAHGITVVLDQPWVGQEIADNPMNVLVVPSPLPVELSLVQ TVGITKFGSYIETGSGLSLGNSWSERLQNIFEFVSNQSGQPSTFSSENKQSVADFVRYLSNPTLKGGIIVEKITGPRSKGHLELRTTNPNDNPSVTFNYF KDPEDLRICVEGMKTIIAVINSKALSKFRYPNLSVQALIDLMLLIPMNLRPKHVNAAYSLEQYCIDTVLTIWHYHGGCPPRKVVDHNYKVIGVEALRVID GSTFYRTPGTNPQATVMMLGRYMGEKIINKR |
Full Sequence |
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Protein Sequence Length: 581 Download |
MGWMLEKFIW AFLVECTFLS GLSHSHQASK YAFVREATSA PPILSYDYIV IGGGTSGCPL 60 AATLSQGARV LVLERGGSPY TNPERINIKN FVNSLADISP SSFSQPFIST DGVLNARARV 120 LGGGSVLNAG FYSRASSEYI RTSGWNESLA EESYKWVERK VVFEPPMLQW QSAVRDGLLE 180 VGVLPYNDFT YDHLNGTKIG GTIFDNKGNR HTAADLLEYA DPKRISVYLH ATVQKILFKY 240 NTGKRRPEAY GVIFRDALGV MHRAYLNTNG KNEIILSAGA IGSPQLLMLS GIGPARHLQA 300 HGITVVLDQP WVGQEIADNP MNVLVVPSPL PVELSLVQTV GITKFGSYIE TGSGLSLGNS 360 WSERLQNIFE FVSNQSGQPS TFSSENKQSV ADFVRYLSNP TLKGGIIVEK ITGPRSKGHL 420 ELRTTNPNDN PSVTFNYFKD PEDLRICVEG MKTIIAVINS KALSKFRYPN LSVQALIDLM 480 LLIPMNLRPK HVNAAYSLEQ YCIDTVLTIW HYHGGCPPRK VVDHNYKVIG VEALRVIDGS 540 TFYRTPGTNP QATVMMLGRY MGEKIINKRF FSGHKSEGIN * 600 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
TIGR01810 | betA | 9.0e-12 | 416 | 569 | 161 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
TIGR01810 | betA | 4.0e-22 | 47 | 319 | 311 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
pfam05199 | GMC_oxred_C | 8.0e-25 | 414 | 558 | 150 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
COG2303 | BetA | 7.0e-49 | 44 | 565 | 575 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
PLN02785 | PLN02785 | 0 | 8 | 569 | 587 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI31862.1 | 0 | 18 | 569 | 19 | 537 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_200008.1 | 0 | 3 | 569 | 7 | 576 | glucose-methanol-choline (GMC) oxidoreductase family protein [Arabidopsis thaliana] |
RefSeq | XP_002267807.1 | 0 | 18 | 569 | 19 | 559 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002267848.1 | 0 | 18 | 569 | 19 | 559 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002510860.1 | 0 | 7 | 570 | 7 | 571 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3red_L | 0 | 23 | 569 | 4 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_K | 0 | 23 | 569 | 4 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_J | 0 | 23 | 569 | 4 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_I | 0 | 23 | 569 | 4 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_H | 0 | 23 | 569 | 4 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |