y
Basic Information | |
---|---|
Species | Phaseolus vulgaris |
Cazyme ID | Phvul.008G017900.1 |
Family | GT47 |
Protein Properties | Length: 526 Molecular Weight: 60076.5 Isoelectric Point: 8.2831 |
Chromosome | Chromosome/Scaffold: 08 Start: 1526296 End: 1527873 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 113 | 463 | 0 |
SCAGQYIYVHDLASRFNEDLVKGCHSLMRWFDMCPYMSNLGLGPKVIEKSKEKVLLKENWYATNQFSLEVIFHNTMKNYKCLTKDSSLASAIYVPYYAGL DVGQYLWGGFNVSTRDASPKELVKWLSQQPEWKRMWGRDHFIVGGRIGWDFKRVTDMNGDWGTKLMLLPEARNMSILLIESAGSEENEFAIPYPTYFHPN KDREIFQWQKKMRDVKRPYLFSFAGAPRPASNNSSSSSIRNEIIKQCQSSRSCKLLNCHDSHYHNNCNDPVQVTKVFQSSVFCIQPPGDSFTRRSTFDSI LAGCIPVFFDPRSAYNQYLWHLPKNGSSYSVYIPITDVTEKRVMINETLSK |
Full Sequence |
---|
Protein Sequence Length: 526 Download |
MDKPPLGKHF DNLRFVFLIS FVFCFSLLLL DYYAAVSDHG IDFLLFHMNG ANHEHMQTMP 60 EPSDSSFIFN ETADCPEKTI HANQNNVSTV PGEVHKRDSV GVVANSPSRN LDSCAGQYIY 120 VHDLASRFNE DLVKGCHSLM RWFDMCPYMS NLGLGPKVIE KSKEKVLLKE NWYATNQFSL 180 EVIFHNTMKN YKCLTKDSSL ASAIYVPYYA GLDVGQYLWG GFNVSTRDAS PKELVKWLSQ 240 QPEWKRMWGR DHFIVGGRIG WDFKRVTDMN GDWGTKLMLL PEARNMSILL IESAGSEENE 300 FAIPYPTYFH PNKDREIFQW QKKMRDVKRP YLFSFAGAPR PASNNSSSSS IRNEIIKQCQ 360 SSRSCKLLNC HDSHYHNNCN DPVQVTKVFQ SSVFCIQPPG DSFTRRSTFD SILAGCIPVF 420 FDPRSAYNQY LWHLPKNGSS YSVYIPITDV TEKRVMINET LSKVPKSEVL AMKKEIIRLI 480 PRIIYRYPSS RLETVEDAFD TAVKGILGRI EATKRDTTKV NHSSS* 540 |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-68 | 113 | 452 | 350 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_002280815.1 | 0 | 112 | 524 | 91 | 494 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002300146.1 | 0 | 1 | 515 | 7 | 490 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002313430.1 | 0 | 95 | 516 | 122 | 534 | glycosyltransferase, CAZy family GT47 [Populus trichocarpa] |
RefSeq | XP_002321098.1 | 0 | 60 | 519 | 8 | 447 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002532518.1 | 0 | 1 | 519 | 1 | 503 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |