Basic Information | |
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Species | Phaseolus vulgaris |
Cazyme ID | Phvul.009G091800.1 |
Family | GT47 |
Protein Properties | Length: 471 Molecular Weight: 54700 Isoelectric Point: 9.1961 |
Chromosome | Chromosome/Scaffold: 09 Start: 14195190 End: 14198929 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 141 | 422 | 0 |
KIFKVFVYPDGDLPIVHDGPCKDIYSIEGRFLHEMEHGVGRFRTNDPTAAHVYFLPFSVTWMVKYLYTPYDVTPLKNFVSDYVRVISTRYPFWNKTQGAD HFMVACHDWGPYASKGNPFLYNTSIRVLCNANTSEGFNPQKDVPLPEIHLYGGEVSPKLLSPPPENAPRRYLAFFAGGMHGPIRPILIHHWENQDNDMRV YQYLPKDLDYYSFMLDSKFCLCPSGYEVASPRIVESIYAECVPVILSKNYTLPFGDVLQWEAFSVQVDVSDIPRLKELLSGI |
Full Sequence |
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Protein Sequence Length: 471 Download |
MKLFRKRLFL FEFLLLFLSL IIIERLLPWQ FIRFTKSNLE YSVSLHQLRR QVSGENQLLR 60 PVKESSHSSN NTVTREVVRM KSREEKREEG LARARAAMRI AALAGGNLTA PTTRDNDDIP 120 AAGFLYRNPL LFYQSYLEME KIFKVFVYPD GDLPIVHDGP CKDIYSIEGR FLHEMEHGVG 180 RFRTNDPTAA HVYFLPFSVT WMVKYLYTPY DVTPLKNFVS DYVRVISTRY PFWNKTQGAD 240 HFMVACHDWG PYASKGNPFL YNTSIRVLCN ANTSEGFNPQ KDVPLPEIHL YGGEVSPKLL 300 SPPPENAPRR YLAFFAGGMH GPIRPILIHH WENQDNDMRV YQYLPKDLDY YSFMLDSKFC 360 LCPSGYEVAS PRIVESIYAE CVPVILSKNY TLPFGDVLQW EAFSVQVDVS DIPRLKELLS 420 GIPEREYRKL KHGVRAARRH FTLNQPAKRF DAFHMILHSI WLRRLDRDLK * 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-65 | 139 | 422 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI21064.1 | 0 | 30 | 469 | 32 | 477 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_197913.4 | 0 | 47 | 469 | 51 | 479 | catalytic [Arabidopsis thaliana] |
RefSeq | XP_002285237.1 | 0 | 139 | 469 | 1 | 333 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002324871.1 | 0 | 139 | 469 | 1 | 333 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002515489.1 | 0 | 14 | 466 | 20 | 477 | catalytic, putative [Ricinus communis] |