Basic Information | |
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Species | Phaseolus vulgaris |
Cazyme ID | Phvul.009G109300.1 |
Family | GT47 |
Protein Properties | Length: 638 Molecular Weight: 73093.7 Isoelectric Point: 9.4375 |
Chromosome | Chromosome/Scaffold: 09 Start: 16392205 End: 16396532 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 306 | 588 | 0 |
ERTLKVYVYREGAKPIMHSPYLLGIYASEGWFMKQMEASKQFVTKDPKKAHLFYLPFSSRMLEETLYVQNSHSSRNLVQYLKNYVDMIAGKHNFWNRTGG ADHFLVACHDWAPKETKKDMARCLRALCNADVKEGFVLGKDVSLPETYVRNAQRPTRNIGGNRVSKRKTLAFFAGGMHGYLRPILLQHWENKDPDMKIFG TLPRSKGNRNYIQYMKSSKYCICAKGYEVNSPRVVEAIFFECVPVIISDNFVPPFFEMLNWESFAVFVLEKDIPNLKSILLSI |
Full Sequence |
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Protein Sequence Length: 638 Download |
MAIGQRQLFS NFSRMGQELF SIFKLEKKRL LGFISITIAI ILVFQYLELP YGAVQPTVFS 60 GNMTPTLDST RFQVVDVPSN SETIKNMTFF NQANSTGENA REIVNITKTS EVKDTISSTG 120 FISEPARESG RSLEFGVTDE SSTEESTQKS NNGSATDQTG NLGLSIYNNN VSHSLSHLAP 180 PSPTNVSQNI TPPMLSNDYD ETEFTEDERF KLVGNNSSIS SMPKETKGSQ IPLLEVTTIS 240 EMNELLLQNR ASYRSMRPRW SLAVDQELLQ TRSEIENAPI INDDVNLYAP LFRNVSRFKR 300 SYELMERTLK VYVYREGAKP IMHSPYLLGI YASEGWFMKQ MEASKQFVTK DPKKAHLFYL 360 PFSSRMLEET LYVQNSHSSR NLVQYLKNYV DMIAGKHNFW NRTGGADHFL VACHDWAPKE 420 TKKDMARCLR ALCNADVKEG FVLGKDVSLP ETYVRNAQRP TRNIGGNRVS KRKTLAFFAG 480 GMHGYLRPIL LQHWENKDPD MKIFGTLPRS KGNRNYIQYM KSSKYCICAK GYEVNSPRVV 540 EAIFFECVPV IISDNFVPPF FEMLNWESFA VFVLEKDIPN LKSILLSIPQ KRYLQMQMMV 600 RKVQQHFLWH RNPVKYDIFH MILHSIWFNR VFTAKAR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-71 | 305 | 588 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_197954.1 | 0 | 15 | 632 | 1 | 650 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002281263.1 | 0 | 15 | 637 | 1 | 669 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309547.1 | 0 | 174 | 637 | 7 | 471 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324801.1 | 0 | 242 | 637 | 1 | 398 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002516500.1 | 0 | 232 | 635 | 51 | 454 | catalytic, putative [Ricinus communis] |