y
Basic Information | |
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Species | Phaseolus vulgaris |
Cazyme ID | Phvul.009G109400.1 |
Family | GT47 |
Protein Properties | Length: 620 Molecular Weight: 69530.4 Isoelectric Point: 8.8862 |
Chromosome | Chromosome/Scaffold: 09 Start: 16406645 End: 16410355 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 289 | 570 | 0 |
KMLKVYIYPDGDRPIFHEPLLDGIYASEGWFMKLMEANKQFVTGDPEKAHLFYIPFSSRLLQQTLYVRNSHKRSNLIEYMKNFVSMIAGKYPFWNRTSGA DHFVVACHDWAPAETRGRMLSCIRALCNADIEVGFKIGKDVSLPETYIRSSENPVKNIGGNPPSQKPILAFFAGGLHGYVRPILLNHWENKEPDMIISET LPHVRGNRNYIQFMKSSKFCICARGHEVNSPRVVEAIFHECIPVIISDNFIPPLFEILNWESFAVFVAEEDIPNLRNILLSI |
Full Sequence |
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Protein Sequence Length: 620 Download |
MDRGFRFLCK AETTRLVSFV GITVAIVLMF QYSELPSSKF LSTVTTKISS FRMDTSSANS 60 KVEGNNMLLN GSNSNSKDAL QDNAVNPQGS LFQNGRDSIT APAPEKAKGL DSVVNFTTRN 120 DGSPMGSAQG MQISLTSQGA ASPQPMVPLP NRTSLDSETD SRSPVVSVIS AATSVKSDTT 180 GSVSKDGNSG SLHGSSNMTV NNGKPVSVKN AKRRPSKVVS ISEMNLLLQN NHAYSQQEKP 240 ARSSAVDLEI LHAKSEILNA PITVNDSRLY PPLYRNVSMF RRSYELMEKM LKVYIYPDGD 300 RPIFHEPLLD GIYASEGWFM KLMEANKQFV TGDPEKAHLF YIPFSSRLLQ QTLYVRNSHK 360 RSNLIEYMKN FVSMIAGKYP FWNRTSGADH FVVACHDWAP AETRGRMLSC IRALCNADIE 420 VGFKIGKDVS LPETYIRSSE NPVKNIGGNP PSQKPILAFF AGGLHGYVRP ILLNHWENKE 480 PDMIISETLP HVRGNRNYIQ FMKSSKFCIC ARGHEVNSPR VVEAIFHECI PVIISDNFIP 540 PLFEILNWES FAVFVAEEDI PNLRNILLSI SEERYLEMHK RVKKVQEHFI WHAEPVKYDL 600 FHMLLHSIWY NRLFQTNQT* 660 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-64 | 287 | 570 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI28021.1 | 0 | 5 | 616 | 7 | 662 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002281263.1 | 0 | 1 | 615 | 1 | 665 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309546.1 | 0 | 209 | 615 | 17 | 413 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002309547.1 | 0 | 155 | 615 | 1 | 467 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002516500.1 | 0 | 177 | 616 | 11 | 453 | catalytic, putative [Ricinus communis] |