| Basic Information | |
|---|---|
| Species | Phaseolus vulgaris |
| Cazyme ID | Phvul.009G160700.1 |
| Family | GT47 |
| Protein Properties | Length: 417 Molecular Weight: 47358.8 Isoelectric Point: 6.9405 |
| Chromosome | Chromosome/Scaffold: 09 Start: 23249724 End: 23254293 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 49 | 344 | 0 |
| RLKVFVYELPSKYNKKILQKDPRCLTHMFAAEIFMHRFLLSSPVRTLNPEEADWFYTPVYTTCDLTPNGLPLPFKSPRMMRSAIQLISSNWPYWNRTEGA DHFFVTPHDFGACFHYQEEKAIERGILPLLQRATLVQTFGQRNHVCLKEGSITIPPYAPPQKMHAHLIPEKTPRSVFVYFRGLFYDVGNDPEGGYYARGA RAAVWENFKDNPLFDISTEHPTTYYEDMQRAVFCLCPLGWAPWSPRLVEAVIFGCIPVIIADDIVLPFADAIPWEEIGVFVDEKDVPQLDSILTSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 417 Download |
| MDFWKVGFLC LLWAASVLAI GAVELGRHRP TERISGSAGD VLEDDPVGRL KVFVYELPSK 60 YNKKILQKDP RCLTHMFAAE IFMHRFLLSS PVRTLNPEEA DWFYTPVYTT CDLTPNGLPL 120 PFKSPRMMRS AIQLISSNWP YWNRTEGADH FFVTPHDFGA CFHYQEEKAI ERGILPLLQR 180 ATLVQTFGQR NHVCLKEGSI TIPPYAPPQK MHAHLIPEKT PRSVFVYFRG LFYDVGNDPE 240 GGYYARGARA AVWENFKDNP LFDISTEHPT TYYEDMQRAV FCLCPLGWAP WSPRLVEAVI 300 FGCIPVIIAD DIVLPFADAI PWEEIGVFVD EKDVPQLDSI LTSIPPEVIL RKQRLLANPS 360 MKQAMLFPQP VQPGDAFHQV LNGLARKLPH DRSVFLKPRE KVLNWTAGPV GDLKPW* 420 |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| pfam03016 | Exostosin | 7.0e-82 | 49 | 344 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAM64940.1 | 0 | 9 | 416 | 8 | 415 | unknown [Arabidopsis thaliana] |
| RefSeq | NP_568941.1 | 0 | 9 | 416 | 8 | 415 | GUT1; catalytic/ glucuronoxylan glucuronosyltransferase [Arabidopsis thaliana] |
| RefSeq | XP_002284685.1 | 0 | 1 | 416 | 1 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002318180.1 | 0 | 1 | 416 | 1 | 417 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002511079.1 | 0 | 1 | 416 | 1 | 417 | catalytic, putative [Ricinus communis] |
