Basic Information | |
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Species | Phaseolus vulgaris |
Cazyme ID | Phvul.009G187300.1 |
Family | GT47 |
Protein Properties | Length: 505 Molecular Weight: 57553.2 Isoelectric Point: 9.7573 |
Chromosome | Chromosome/Scaffold: 09 Start: 27685802 End: 27689490 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 114 | 431 | 0 |
LRVFMYDLPPEFHFGLLGWKGSLNQTWPEVDNPEGIPRYPGGLNLQHSMEYWLTLDLLSSNTAKVGHSCSAIRVQDSSQADVIFVPFFSSLSYNRHSKLH GEEKVSVNKMLQDKLVQFLMNRKEWKRSGGKDHLIIAHHPNSLLDARRKLGSAMLVLADFGRYPAQLANIKKDVIAPYRHLVGTIPRAKSASYEERTTLV YFQGAIYRKDGGAIRQELYYLLKEEKDVHFSFGSIGGNGIKQASQGMALSKFCLNIAGDTPSSNRLFDAIASHCVPVIISDEIELPFEDVLDYSEFSVFV RASDAVKKGYLLNVLRSI |
Full Sequence |
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Protein Sequence Length: 505 Download |
MSEKIMFHSR FIFYVMIISM FLLVMSSLFL LQFSSHSLIP RSVLELILVN NASQYFMPNM 60 KREQIVVPPC PSGDLKFQSQ KPRESDCQAS DSSQKTSSVG QQMNVASHPV RPLLRVFMYD 120 LPPEFHFGLL GWKGSLNQTW PEVDNPEGIP RYPGGLNLQH SMEYWLTLDL LSSNTAKVGH 180 SCSAIRVQDS SQADVIFVPF FSSLSYNRHS KLHGEEKVSV NKMLQDKLVQ FLMNRKEWKR 240 SGGKDHLIIA HHPNSLLDAR RKLGSAMLVL ADFGRYPAQL ANIKKDVIAP YRHLVGTIPR 300 AKSASYEERT TLVYFQGAIY RKDGGAIRQE LYYLLKEEKD VHFSFGSIGG NGIKQASQGM 360 ALSKFCLNIA GDTPSSNRLF DAIASHCVPV IISDEIELPF EDVLDYSEFS VFVRASDAVK 420 KGYLLNVLRS IKRDEWNKMW EKLKEITPHF EYQYPSQPGD AVNMIWRQVS TKISSIRFNL 480 HRKNRYQRSQ LRAKTNLNSE ILGR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-57 | 114 | 431 | 327 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_565089.1 | 0 | 1 | 491 | 4 | 454 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002284930.1 | 0 | 1 | 496 | 1 | 455 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
RefSeq | XP_002284932.1 | 0 | 83 | 496 | 3 | 416 | PREDICTED: hypothetical protein isoform 2 [Vitis vinifera] |
RefSeq | XP_002320639.1 | 0 | 114 | 488 | 3 | 374 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002514760.1 | 0 | 34 | 492 | 34 | 490 | catalytic, putative [Ricinus communis] |