| Basic Information | |
|---|---|
| Species | Phaseolus vulgaris |
| Cazyme ID | Phvul.010G122400.1 |
| Family | GT68 |
| Protein Properties | Length: 545 Molecular Weight: 61950.8 Isoelectric Point: 6.1722 |
| Chromosome | Chromosome/Scaffold: 10 Start: 39246413 End: 39249402 |
| Description | O-fucosyltransferase family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT68 | 225 | 519 | 0 |
| LNRILVIPSSKVDYRFDRVVDIDRINKCLGKKVVVSFEDFSNLKKGHMHIDKFLCYFSKPSPCYLDDEWLKKLEGLGLTMNKPEVVWDEDTRNPKNKTVQ DVLGKFSYDDDVMAIGDVFYAEVEPEWVMQPGGPIAHQCKTLIEPNRLISLTAQRFIQTFLGKNFVALHFRRHGFLKFCNAKKPSCFFPIPQAAECILRV VERADAPIVYLSTDAAESETGLLQSLVVLNGRPVPLVIRPARNSAEKWDALLYRHGLDGDTQVEAMLDKTICAMSSVFIGAPGSTFTEDILRLRR | |||
| Full Sequence |
|---|
| Protein Sequence Length: 545 Download |
| MHMDSSSDEE EDDHRNLVDH NHRKPPSPHL AAAFHVEDPS SRFSHVNSRF QKKYIVAILA 60 ILLVILFFSV ADFHSLSSSS SFQFDSITDR MKESELRAIN LLRRQQLGLL TAWNTTRQSN 120 VSDPNQLEDL KSTLFKQISL NREIEQILLN PHSMGNSVEP EFDLNATLNG VIYDRCRTVD 180 QNLSERRTIQ WNPRDGKFLL AICVSGQMSN HLICLEKHIF FAALLNRILV IPSSKVDYRF 240 DRVVDIDRIN KCLGKKVVVS FEDFSNLKKG HMHIDKFLCY FSKPSPCYLD DEWLKKLEGL 300 GLTMNKPEVV WDEDTRNPKN KTVQDVLGKF SYDDDVMAIG DVFYAEVEPE WVMQPGGPIA 360 HQCKTLIEPN RLISLTAQRF IQTFLGKNFV ALHFRRHGFL KFCNAKKPSC FFPIPQAAEC 420 ILRVVERADA PIVYLSTDAA ESETGLLQSL VVLNGRPVPL VIRPARNSAE KWDALLYRHG 480 LDGDTQVEAM LDKTICAMSS VFIGAPGSTF TEDILRLRRG WETASICDEY LCQGEEPDIV 540 AENE* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd11548 | NodZ_like | 0.005 | 364 | 520 | 168 | + Alpha 1,6-fucosyltransferase similar to Bradyrhizobium NodZ. Bradyrhizobium NodZ is an alpha 1,6-fucosyltransferase involved in the biosynthesis of the nodulation factor, a lipo-chitooligosaccharide formed by three-to-six beta-1,4-linked N-acetyl-d-glucosamine (GlcNAc) residues and a fatty acid acyl group attached to the nitrogen atom at the non-reducing end. NodZ transfers L-fucose from the GDP-beta-L-fucose donor to the reducing residue of the chitin oligosaccharide backbone, before the attachment of a fatty acid group. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| pfam10250 | O-FucT | 8.0e-5 | 221 | 519 | 333 | + GDP-fucose protein O-fucosyltransferase. This is a family of conserved proteins representing the enzyme responsible for adding O-fucose to EGF (epidermal growth factor-like) repeats. Six highly conserved cysteines are present in O-FucT-1 as well as a DXD-like motif (ERD), conserved in mammals, Drosophila, and C. elegans. Both features are characteristic of several glycosyltransferase families. The enzyme is a membrane-bound protein released by proteolysis and, as for most glycosyltransferases, is strongly activated by manganese. | ||
| cd11296 | O-FucT_like | 5.0e-5 | 198 | 239 | 42 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| cd11298 | O-FucT-2 | 2.0e-7 | 371 | 511 | 141 | + GDP-fucose protein O-fucosyltransferase 2. O-FucT-2 adds O-fucose to thrombospondin type 1 repeats (TSRs), and appears conserved in bilateria. The O-fucosylation of TSRs appears to play a role in regulating secretion of metalloproteases of the ADAMTS superfamily. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| cd11296 | O-FucT_like | 3.0e-16 | 360 | 519 | 170 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAM66093.1 | 0 | 3 | 544 | 1 | 566 | unknown [Arabidopsis thaliana] |
| RefSeq | NP_173170.2 | 0 | 3 | 544 | 1 | 564 | unknown protein [Arabidopsis thaliana] |
| RefSeq | NP_199853.1 | 0 | 3 | 544 | 1 | 566 | unknown protein [Arabidopsis thaliana] |
| RefSeq | XP_002264087.1 | 0 | 3 | 544 | 1 | 559 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002303337.1 | 0 | 3 | 544 | 1 | 527 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3emj_L | 0.003 | 222 | 270 | 100 | 148 | A Chain A, Fructose-1,6-Bisphosphate AldolasePHOSPHATASE FROM THERMOPROTEUS Neutrophilus, Ligand Free |
| PDB | 3emj_K | 0.003 | 222 | 270 | 100 | 148 | A Chain A, Fructose-1,6-Bisphosphate AldolasePHOSPHATASE FROM THERMOPROTEUS Neutrophilus, Ligand Free |
| PDB | 3emj_J | 0.003 | 222 | 270 | 100 | 148 | A Chain A, Fructose-1,6-Bisphosphate AldolasePHOSPHATASE FROM THERMOPROTEUS Neutrophilus, Ligand Free |
| PDB | 3emj_I | 0.003 | 222 | 270 | 100 | 148 | A Chain A, Fructose-1,6-Bisphosphate AldolasePHOSPHATASE FROM THERMOPROTEUS Neutrophilus, Ligand Free |
| PDB | 3emj_H | 0.003 | 222 | 270 | 100 | 148 | A Chain A, Fructose-1,6-Bisphosphate AldolasePHOSPHATASE FROM THERMOPROTEUS Neutrophilus, Ligand Free |
