Basic Information | |
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Species | Phaseolus vulgaris |
Cazyme ID | Phvul.010G139000.1 |
Family | AA3 |
Protein Properties | Length: 627 Molecular Weight: 68951.9 Isoelectric Point: 8.8896 |
Chromosome | Chromosome/Scaffold: 10 Start: 41096426 End: 41103291 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 84 | 617 | 0 |
PSISTTTSNNVYDYIILGGGTAGCPLAATLSQNYSVLVLERGGVPFTNPNVSFLENFHITLADISPTSASQYFISTDGVYNSRARVLGGGSSINAGFYTR ANPSFIEKVGWDAKLVNQSYPWVEKQIVHRPTFSPYQRAVRDSLLDSGVSPFNGFTYDHLYGTKVGGTIFDRFGRRHTAAELLASGNHEKLTVLVYATVQ KIVFDTKGKKPKAVGVIFQDENGKQHEAILANDRHSEVIMSTGAIGTPQLLMLSGIGPKEELQKLNIPVVLDNQFVGKGMVDNPMNTMFVPSKRPVHQSL IETVGITKMGVYIEASSGFSQSNDSIHCHHGIMSAEIGQLSTIPPKQRSPEAVQEFVKNKRDLPIEAFKGGFILSKVANPWSVGELKLVNTNVKDNPAVT FNYFSHPYDLERCVKGIRLAIKVVQSKHFTNYTMCDKKTAEELLNLTVKANVNFIPKHVKDTKSLKQFCKDTVITIWHYHGGCHVGKVVNPDYMVLGVDR LRVVDGSTFDESPGTNPQATVMMMGRYMGLKILR |
Full Sequence |
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Protein Sequence Length: 627 Download |
MMHTQTKANE SKPLIGWEEA ASSEREKDCV FSGPSDSMAS VGALRFLFCL ALCLCNFLPS 60 CQGSSHWHEN KYPFIRNASS FSSPSISTTT SNNVYDYIIL GGGTAGCPLA ATLSQNYSVL 120 VLERGGVPFT NPNVSFLENF HITLADISPT SASQYFISTD GVYNSRARVL GGGSSINAGF 180 YTRANPSFIE KVGWDAKLVN QSYPWVEKQI VHRPTFSPYQ RAVRDSLLDS GVSPFNGFTY 240 DHLYGTKVGG TIFDRFGRRH TAAELLASGN HEKLTVLVYA TVQKIVFDTK GKKPKAVGVI 300 FQDENGKQHE AILANDRHSE VIMSTGAIGT PQLLMLSGIG PKEELQKLNI PVVLDNQFVG 360 KGMVDNPMNT MFVPSKRPVH QSLIETVGIT KMGVYIEASS GFSQSNDSIH CHHGIMSAEI 420 GQLSTIPPKQ RSPEAVQEFV KNKRDLPIEA FKGGFILSKV ANPWSVGELK LVNTNVKDNP 480 AVTFNYFSHP YDLERCVKGI RLAIKVVQSK HFTNYTMCDK KTAEELLNLT VKANVNFIPK 540 HVKDTKSLKQ FCKDTVITIW HYHGGCHVGK VVNPDYMVLG VDRLRVVDGS TFDESPGTNP 600 QATVMMMGRY MGLKILRDRL GKLAGI* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam05199 | GMC_oxred_C | 2.0e-27 | 463 | 608 | 151 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
TIGR03970 | Rv0697 | 1.0e-33 | 96 | 608 | 576 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
TIGR01810 | betA | 6.0e-39 | 96 | 608 | 574 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
COG2303 | BetA | 9.0e-53 | 92 | 619 | 582 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
PLN02785 | PLN02785 | 0 | 60 | 626 | 569 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI35951.1 | 0 | 38 | 626 | 1 | 593 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002275841.1 | 0 | 48 | 626 | 6 | 584 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002327436.1 | 0 | 91 | 626 | 13 | 547 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002329018.1 | 0 | 58 | 626 | 20 | 591 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002527404.1 | 0 | 60 | 625 | 29 | 596 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3gdp_B | 0 | 95 | 619 | 27 | 517 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
PDB | 3gdp_A | 0 | 95 | 619 | 27 | 517 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
PDB | 3gdn_B | 0 | 95 | 619 | 27 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 3gdn_A | 0 | 95 | 619 | 27 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 1ju2_B | 0 | 95 | 619 | 27 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO796743 | 532 | 96 | 627 | 0 |
HO852522 | 376 | 247 | 622 | 0 |
ES808127 | 414 | 191 | 596 | 0 |
CK271873 | 317 | 93 | 409 | 0 |
CV530727 | 287 | 297 | 583 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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