| Basic Information | |
|---|---|
| Species | Phaseolus vulgaris |
| Cazyme ID | Phvul.010G162900.1 |
| Family | AA3 |
| Protein Properties | Length: 550 Molecular Weight: 60512 Isoelectric Point: 8.8332 |
| Chromosome | Chromosome/Scaffold: 10 Start: 43008118 End: 43010019 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA3 | 56 | 546 | 0 |
| VEEYYDYIIVGGGTAGCPLAATLSHSFKVLVLERGGVGSGNPNLMNQEGFLNNLLNVETEDSPAQAFISEEGVPNARGRVLGGSSAINAGFYSRAHRDFF ERSGLPWDLALVNQSYQWVEKEIVFRPKLKTWQSSVRDALLETGVTPYNGFTLDHAKGTKIGGSTFDSSGRRHTSADLLRHARPSNIKVAVHATVERLLL AGSTAIGALFRDQRGRHHRAFLQEHGEVILSAGAIGSPQLLLLSGIGSRPYLSSWGIPVAHHLPYVGHFLYDNPRNGITILPSLPLDHSLIQVVGITDSG AYIEAASNVVPFISPRHNAFVRSPLYLTVATLISKISGPLSAGFLRLASTDVDANPRVRFNYFDNLVDLERCVNGSRKIAEILRSRALKDFKFSNWFGEA DFRFIGPALPLHQTEFPRMADFCRRTVSTIWHYHGGCVVGRVVDPHLKVIGVDSLRIVDGSVFSVSPGTNPQATLMMLGRYFGLKMITERN | |||
| Full Sequence |
|---|
| Protein Sequence Length: 550 Download |
| MERPISSVHL EYVALFILCT TLFASATTSQ HQESQTRQHK EPSYLKMVVN ATELPVEEYY 60 DYIIVGGGTA GCPLAATLSH SFKVLVLERG GVGSGNPNLM NQEGFLNNLL NVETEDSPAQ 120 AFISEEGVPN ARGRVLGGSS AINAGFYSRA HRDFFERSGL PWDLALVNQS YQWVEKEIVF 180 RPKLKTWQSS VRDALLETGV TPYNGFTLDH AKGTKIGGST FDSSGRRHTS ADLLRHARPS 240 NIKVAVHATV ERLLLAGSTA IGALFRDQRG RHHRAFLQEH GEVILSAGAI GSPQLLLLSG 300 IGSRPYLSSW GIPVAHHLPY VGHFLYDNPR NGITILPSLP LDHSLIQVVG ITDSGAYIEA 360 ASNVVPFISP RHNAFVRSPL YLTVATLISK ISGPLSAGFL RLASTDVDAN PRVRFNYFDN 420 LVDLERCVNG SRKIAEILRS RALKDFKFSN WFGEADFRFI GPALPLHQTE FPRMADFCRR 480 TVSTIWHYHG GCVVGRVVDP HLKVIGVDSL RIVDGSVFSV SPGTNPQATL MMLGRYFGLK 540 MITERNDYK* |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| PRK02106 | PRK02106 | 6.0e-34 | 57 | 327 | 332 | + choline dehydrogenase; Validated |
| TIGR03970 | Rv0697 | 9.0e-41 | 61 | 534 | 520 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. |
| TIGR01810 | betA | 4.0e-41 | 61 | 534 | 547 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. |
| COG2303 | BetA | 1.0e-50 | 60 | 535 | 540 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] |
| PLN02785 | PLN02785 | 0 | 12 | 545 | 582 | + Protein HOTHEAD |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0009055 | electron carrier activity |
| GO:0016491 | oxidoreductase activity |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABE65766.1 | 0 | 30 | 545 | 24 | 550 | mandelonitrile lyase [Arabidopsis thaliana] |
| GenBank | ACN31582.1 | 0 | 33 | 549 | 26 | 586 | unknown [Zea mays] |
| RefSeq | NP_177448.1 | 0 | 30 | 545 | 24 | 550 | (R)-mandelonitrile lyase, putative / (R)-oxynitrilase, putative [Arabidopsis thaliana] |
| RefSeq | XP_002277531.1 | 0 | 1 | 545 | 1 | 546 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002311915.1 | 0 | 41 | 545 | 1 | 517 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3gdp_B | 0 | 26 | 546 | 2 | 518 | A Chain A, Crystal Structure Of Cytotoxin Protein Suilysin From Streptococcus Suis |
| PDB | 3gdp_A | 0 | 26 | 546 | 2 | 518 | A Chain A, Crystal Structure Of Cytotoxin Protein Suilysin From Streptococcus Suis |
| PDB | 3gdn_B | 0 | 26 | 546 | 2 | 518 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 3gdn_A | 0 | 26 | 546 | 2 | 518 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 1ju2_B | 0 | 26 | 546 | 2 | 518 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
