Basic Information | |
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Species | Phaseolus vulgaris |
Cazyme ID | Phvul.011G019900.1 |
Family | GT47 |
Protein Properties | Length: 501 Molecular Weight: 56627.5 Isoelectric Point: 9.287 |
Chromosome | Chromosome/Scaffold: 11 Start: 1570141 End: 1575208 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 110 | 420 | 0 |
LRVYVYDMPPKFTYDLLRLFKKTYRDTSNLTSNGSPVHRLIEQHSIDYWLWADLIAPQSERLLNSVVRVHRQEEADLFYVPFFTTISFFLMEKQQCKALY REALKWITDQPAWKRSGGRDHIIPVHHPWSFKSVRKFVKNAIWLLPDMDSTGNWYKPGQVFLEKDLILPYVPNLDLCDARCLTESRPKRNMLLFFRGRLK RNAGGKIRSKLVAELSGADGVSIEEGTAGDGGKEAAQIGMRKSLFCLSPAGDTPSSARLFDAIVSGCIPVIISDELELPFEGILDYRKIALFISSNDAVK PGWLLKYLKGI |
Full Sequence |
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Protein Sequence Length: 501 Download |
MAGKYIPRSK SRTTLFLFLL AFSLLFILFS LSPLRSPLLS PTNVHVPDAE TSFVASLDRF 60 LAAAPSPHSL SDDTAHAGQE DLITKLDDAV YGSEMDRLYS DPYYPLSLPL RVYVYDMPPK 120 FTYDLLRLFK KTYRDTSNLT SNGSPVHRLI EQHSIDYWLW ADLIAPQSER LLNSVVRVHR 180 QEEADLFYVP FFTTISFFLM EKQQCKALYR EALKWITDQP AWKRSGGRDH IIPVHHPWSF 240 KSVRKFVKNA IWLLPDMDST GNWYKPGQVF LEKDLILPYV PNLDLCDARC LTESRPKRNM 300 LLFFRGRLKR NAGGKIRSKL VAELSGADGV SIEEGTAGDG GKEAAQIGMR KSLFCLSPAG 360 DTPSSARLFD AIVSGCIPVI ISDELELPFE GILDYRKIAL FISSNDAVKP GWLLKYLKGI 420 RPAHIKEMQQ NLAKYSRHFL YSSPAQPLGP EDLVWKMMAG KLVNIKLHTR RSQRVVEGSR 480 NLCTCECRPA NITNTASMIS * |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-69 | 109 | 420 | 320 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_001141657.1 | 0 | 40 | 493 | 49 | 494 | hypothetical protein LOC100273782 [Zea mays] |
RefSeq | NP_197191.1 | 0 | 7 | 487 | 15 | 495 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002285599.1 | 0 | 50 | 494 | 63 | 512 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325382.1 | 0 | 50 | 493 | 58 | 501 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002520033.1 | 0 | 51 | 494 | 58 | 503 | catalytic, putative [Ricinus communis] |