y
Basic Information | |
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Species | Phaseolus vulgaris |
Cazyme ID | Phvul.011G170300.1 |
Family | GT20 |
Protein Properties | Length: 926 Molecular Weight: 104508 Isoelectric Point: 7.9991 |
Chromosome | Chromosome/Scaffold: 11 Start: 44107559 End: 44125848 |
Description | trehalose-6-phosphate synthase |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 86 | 554 | 0 |
LRQRLLVVANRLPVSAVRKGEDVWSLEISAGGLVSALLGVKEFEARWIGWAGVNVPDEIGQKALTKALAEKRCIPVFLDEEIVHQYYNGYCNNILWPLFH YLGLPQEDRLATTRSFQSQFEAYEKANQMFADVVNKHYEEGDVVWCHDYHLMSLPKCLKKHNKNMKVGWFLHTPFPSSEIHRTLPSRSELLHFVLAADLV GFHTYDYARHFVSACTRILGLEGTPYGVEYQGKLTRVAAFPIGIDSERFIRALDLPRVQDHIKELQERFKGRKVMLGVDRLDMIKGIPQKILAFEKFLEE DPYWRDKVVLLQIAVPTRTDVPEYQKLTSQVHEIVGRINGRFGTLTTVPIHHLDRSLDFYQLCALYAVTDVALVTSLRDGMNLVSYEFVACQEKKKGVLI LSEFAGAAQSLGAGAILVNPWNVTEVAAAIARALKMPSAEREKRHKHNFLHVTSHTAQEWAGTFVSELN |
Full Sequence |
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Protein Sequence Length: 926 Download |
MPGNKYTGNS NQIPGRVERL LRERELRKSG RVIQLKEGNE SNGKSGEALE KEKVRLREEE 60 SAAVDGGVEG SRVKEVGEER HETKALRQRL LVVANRLPVS AVRKGEDVWS LEISAGGLVS 120 ALLGVKEFEA RWIGWAGVNV PDEIGQKALT KALAEKRCIP VFLDEEIVHQ YYNGYCNNIL 180 WPLFHYLGLP QEDRLATTRS FQSQFEAYEK ANQMFADVVN KHYEEGDVVW CHDYHLMSLP 240 KCLKKHNKNM KVGWFLHTPF PSSEIHRTLP SRSELLHFVL AADLVGFHTY DYARHFVSAC 300 TRILGLEGTP YGVEYQGKLT RVAAFPIGID SERFIRALDL PRVQDHIKEL QERFKGRKVM 360 LGVDRLDMIK GIPQKILAFE KFLEEDPYWR DKVVLLQIAV PTRTDVPEYQ KLTSQVHEIV 420 GRINGRFGTL TTVPIHHLDR SLDFYQLCAL YAVTDVALVT SLRDGMNLVS YEFVACQEKK 480 KGVLILSEFA GAAQSLGAGA ILVNPWNVTE VAAAIARALK MPSAEREKRH KHNFLHVTSH 540 TAQEWAGTFV SELNDTVIEA QLRTRQVPPQ LPTKAAIESY QQSTNRLLIL GFSGTLTEPV 600 EKTGDQIKEM ELKVHPKLRQ PLTALCSDPN TTVVVLSGSG RQVLDDNFKE YDMWLAAENG 660 MFLHPSKGEW MTTMPEHLNM EWLDSVKHVF EYFTERTPRS HFDFEERETS LVWNYKYADV 720 EFGKLQARDM LQHLWTGPIS NASVEVVQGT RSVEVRAVGV TKGAAIDRIL GEIVHSKSMT 780 SPIDYVLCIG HFLGKDEDIY SFFEPDLPSI GVGLPRSKVT TEGVKFPVER KPSLKVPATK 840 SGPKSSQNKA TRPLSNSEKK TNNHISITPR KAASEKVSWN VLDLKKENYF SCAVGRTRTN 900 ARYTFDSSDD VVSFLKELAN ASFRM* 960 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN03064 | PLN03064 | 0 | 1 | 922 | 933 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN03063 | PLN03063 | 0 | 87 | 925 | 839 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
TIGR02400 | trehalose_OtsA | 0 | 89 | 555 | 469 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming]. This enzyme catalyzes the key, penultimate step in biosynthesis of trehalose, a compatible solute made as an osmoprotectant in some species in all three domains of life. The gene symbol OtsA stands for osmotically regulated trehalose synthesis A. Trehalose helps protect against both osmotic and thermal stresses, and is made from two glucose subunits. This model excludes glucosylglycerol-phosphate synthase, an enzyme of an analogous osmoprotectant system in many cyanobacterial strains. This model does not identify archaeal examples, as they are more divergent than glucosylglycerol-phosphate synthase. Sequences that score in the gray zone between the trusted and noise cutoffs include a number of yeast multidomain proteins in which the N-terminal domain may be functionally equivalent to this family. The gray zone also includes the OtsA of Cornyebacterium glutamicum (and related species), shown to be responsible for synthesis of only trace amounts of trehalose while the majority is synthesized by the TreYZ pathway; the significance of OtsA in this species is unclear (see Wolf, et al., PMID:12890033) [Cellular processes, Adaptations to atypical conditions]. | ||
PRK14501 | PRK14501 | 0 | 89 | 790 | 709 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
pfam00982 | Glyco_transf_20 | 0 | 88 | 555 | 474 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABO61742.1 | 0 | 1 | 921 | 1 | 919 | trehalose-phosphate synthase 1 [Solanum lycopersicum] |
EMBL | CAN79485.1 | 0 | 1 | 921 | 1 | 909 | hypothetical protein [Vitis vinifera] |
RefSeq | XP_002285632.1 | 0 | 1 | 921 | 1 | 923 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002331300.1 | 0 | 1 | 922 | 1 | 921 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002531237.1 | 0 | 1 | 922 | 1 | 923 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1gz5_D | 0 | 89 | 557 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_C | 0 | 89 | 557 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_B | 0 | 89 | 557 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_A | 0 | 89 | 557 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 2wtx_D | 0 | 89 | 565 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
CV711307 | 293 | 87 | 379 | 0 |
CX546763 | 303 | 77 | 378 | 0 |
ES813375 | 409 | 450 | 848 | 0 |
DW069910 | 288 | 175 | 462 | 0 |
FE703590 | 263 | 466 | 728 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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