Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.001G120800.1 |
Family | GT47 |
Protein Properties | Length: 450 Molecular Weight: 51661 Isoelectric Point: 6.773 |
Chromosome | Chromosome/Scaffold: 01 Start: 9729119 End: 9730701 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 33 | 388 | 0 |
CSNRWIHVRSLPPRFNLDLLANCSEYPLFNNFCPYLANHGLGPRTHNKSQSWYRTNPLLLELIFHHRMLEYPCLTSDPNQANAIYLPYYAAIDALRYLYG PEVNSSMEHGLELYDYLQDNEGWIWSRNHGADHFLVMSRPAWDFSQSVDVDPPIWGTSFLELPEFYNVTVLIVEGRAWPWQEQAVPYLTSFHPPNLGFLE SWIKRVKASKRTTLMLFAGGGGVGSTPNIRRSIRNECESSSSDIYVNNVEGFDYPKMRKVCDIVDCSNGICEHDPIRYMRPMLQATFCLQPPGDTPTRRS TFDGIIAGCIPVFFEEQSAKSQYGWHLPEEMYRDFAVFIPKEDVVFKGLRILDVLT |
Full Sequence |
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Protein Sequence Length: 450 Download |
MACKTTSFLC FCLLLISIDS IISQDITDTE RGCSNRWIHV RSLPPRFNLD LLANCSEYPL 60 FNNFCPYLAN HGLGPRTHNK SQSWYRTNPL LLELIFHHRM LEYPCLTSDP NQANAIYLPY 120 YAAIDALRYL YGPEVNSSME HGLELYDYLQ DNEGWIWSRN HGADHFLVMS RPAWDFSQSV 180 DVDPPIWGTS FLELPEFYNV TVLIVEGRAW PWQEQAVPYL TSFHPPNLGF LESWIKRVKA 240 SKRTTLMLFA GGGGVGSTPN IRRSIRNECE SSSSDIYVNN VEGFDYPKMR KVCDIVDCSN 300 GICEHDPIRY MRPMLQATFC LQPPGDTPTR RSTFDGIIAG CIPVFFEEQS AKSQYGWHLP 360 EEMYRDFAVF IPKEDVVFKG LRILDVLTGI PRNEVRRMRE RVIELIPRVL YRKHGSSSGL 420 RARKDAFDIA VEGALQRINS RLKARDFDQ* |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
pfam03016 | Exostosin | 9.0e-52 | 33 | 377 | 358 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_193989.1 | 0 | 21 | 442 | 25 | 435 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002267390.1 | 0 | 33 | 443 | 33 | 439 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002304426.1 | 0 | 16 | 442 | 12 | 429 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002329867.1 | 0 | 1 | 449 | 1 | 439 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002529790.1 | 0 | 1 | 449 | 1 | 456 | catalytic, putative [Ricinus communis] |