Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.001G381900.1 |
Family | GT47 |
Protein Properties | Length: 488 Molecular Weight: 55754.9 Isoelectric Point: 8.9397 |
Chromosome | Chromosome/Scaffold: 01 Start: 39774835 End: 39776298 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 91 | 417 | 0 |
GMSVYLYDMPAEFNKGLLKDCSHLNPYTDMCPHVANRGLGQPLSYMAESAVATTWFATHQFIAEMIFHARMENHPCRVLDPINAKLFYVPFYGGLDASSK FHDANLTARDELAVRLADYLRSKPWWERHHGKDHFLVLGRTAWDFLRRNNNFGNSLLNLPDVQNMSVLTVERNPWDRVHNQHGIPYPSYFHPYTSHEMMT WQNKMRQSSRPHLFSFIGGPRRGVEKAAVRDELIRQCSESGRCKLLKCGKGPSKCHYPIEVLKVMSQSQFCLQAPGDSFTRRSTFDSVLAGCIPVFFSPH TVYTQYEWFFPAGDAREYSVYIDENAL |
Full Sequence |
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Protein Sequence Length: 488 Download |
MVVKKKSISS ASPWTEKGKY SKTNEIHYSF LKPQLRHALL LCFLLSVWFV ILRCFLLSSS 60 TSENNIEKLN VDEKAPKTTS KSSAISKCEG GMSVYLYDMP AEFNKGLLKD CSHLNPYTDM 120 CPHVANRGLG QPLSYMAESA VATTWFATHQ FIAEMIFHAR MENHPCRVLD PINAKLFYVP 180 FYGGLDASSK FHDANLTARD ELAVRLADYL RSKPWWERHH GKDHFLVLGR TAWDFLRRNN 240 NFGNSLLNLP DVQNMSVLTV ERNPWDRVHN QHGIPYPSYF HPYTSHEMMT WQNKMRQSSR 300 PHLFSFIGGP RRGVEKAAVR DELIRQCSES GRCKLLKCGK GPSKCHYPIE VLKVMSQSQF 360 CLQAPGDSFT RRSTFDSVLA GCIPVFFSPH TVYTQYEWFF PAGDAREYSV YIDENALKTG 420 NGSKRVVSIE EELFKIEREQ VERMRSAVIN LMPRLTYAHP NATDLGFQDA VDVALEALWA 480 KRLKLNV* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-66 | 91 | 436 | 359 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAC42883.1 | 0 | 76 | 487 | 54 | 451 | unknown protein [Arabidopsis thaliana] |
RefSeq | NP_177014.1 | 0 | 76 | 487 | 54 | 451 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002270383.1 | 0 | 67 | 478 | 95 | 495 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002300452.1 | 0 | 88 | 487 | 1 | 400 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002336132.1 | 0 | 66 | 487 | 1 | 421 | predicted protein [Populus trichocarpa] |