| Basic Information | |
|---|---|
| Species | Populus trichocarpa |
| Cazyme ID | Potri.001G462500.1 |
| Family | AA7 |
| Protein Properties | Length: 547 Molecular Weight: 62314.1 Isoelectric Point: 9.2072 |
| Chromosome | Chromosome/Scaffold: 01 Start: 49658499 End: 49662020 |
| Description | FAD-binding Berberine family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| AA7 | 66 | 224 | 0 |
| NLRFNMSTTPKPLLILTALHESHVQAAISYAREHNLQMKIRSGGHDYEGVSYVSDVPFFVLDMFNLRSIDVDVASETAWIQVGATLGEVYYRVSEKSQAH GFPASVEPTVGVGGHFGGGGYGNMMRKYGLSVDNIIDAKMVDVKGRLLDRKSMGEDLFW | |||
| Full Sequence |
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| Protein Sequence Length: 547 Download |
| MLRSKMFALL SVFLLSISWE ATSDLDHENF LHCLLNHSQP SYPISTAIYT PNNESYSSVL 60 QSYIRNLRFN MSTTPKPLLI LTALHESHVQ AAISYAREHN LQMKIRSGGH DYEGVSYVSD 120 VPFFVLDMFN LRSIDVDVAS ETAWIQVGAT LGEVYYRVSE KSQAHGFPAS VEPTVGVGGH 180 FGGGGYGNMM RKYGLSVDNI IDAKMVDVKG RLLDRKSMGE DLFWDGDAAR VFFDVRHWAI 240 TGGGGSSFGV VLAYKINIVR VPEVVTVFLV RRNVDQNATD IVEQWQQVAY NIDDDLFIRL 300 TMNVVNSTTR ISEKTVRTTF RALFLGDSER LLSFTNASFP KLGLLRSDCT EMSWLESVLF 360 WTDPPLGTPT DLLRRTPPSL VHFKRKSDYV QKPIPRDGLE GIWKKMIELQ VPQLTFNPYG 420 GKMWEIPATE RPFPHRAGNL WKVQYATDWN KGGQGKANYY IDLTRQLYSY MTPFVSKNPR 480 QAFLNYRDLD LGINHNGKES YLEGRVYGIK YFQENFNRLV KIKTKVDPGN FFRNEQSIPT 540 FPYRKK* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG2266 | COG2266 | 0.006 | 62 | 138 | 83 | + GTP:adenosylcobinamide-phosphate guanylyltransferase [Coenzyme metabolism] | ||
| COG0277 | GlcD | 4.0e-11 | 77 | 541 | 485 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
| pfam08031 | BBE | 1.0e-15 | 482 | 539 | 58 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. | ||
| pfam01565 | FAD_binding_4 | 2.0e-19 | 77 | 214 | 139 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
| GO:0016491 | oxidoreductase activity |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN80091.1 | 0 | 21 | 543 | 23 | 531 | hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002299026.1 | 0 | 6 | 542 | 1 | 524 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002299027.1 | 0 | 71 | 546 | 1 | 462 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002333959.1 | 0 | 8 | 546 | 10 | 535 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523151.1 | 0 | 21 | 545 | 28 | 540 | Reticuline oxidase precursor, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3vte_A | 0 | 28 | 542 | 5 | 514 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
| PDB | 4dns_B | 0 | 27 | 539 | 10 | 494 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 4dns_A | 0 | 27 | 539 | 10 | 494 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3tsj_B | 0 | 28 | 539 | 9 | 494 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3tsj_A | 0 | 28 | 539 | 9 | 494 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| cannabinoid biosynthesis | RXN-7854 | EC-1.21.3 | tetrahydrocannabinolic acid synthase |
