y
Basic Information | |
---|---|
Species | Populus trichocarpa |
Cazyme ID | Potri.001G467000.1 |
Family | CBM57 |
Protein Properties | Length: 843 Molecular Weight: 93232.5 Isoelectric Point: 5.9641 |
Chromosome | Chromosome/Scaffold: 01 Start: 50018650 End: 50022657 |
Description | hercules receptor kinase 2 |
View CDS |
External Links |
---|
NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
CBM57 | 223 | 376 | 1.2e-21 |
YRLNVGGQEIKPDQDSDLWRKWEVDSSYMITADAGVEIKNSSNVTYASNNDSSVAPLLVYETARIMSNTEVLEKKFNMSWKFEVDPDFDYLIRLHFCELV YDKANQRIFKVYINNKTAADNFDVYARSGGKNIAYHQDYFDAISAKINTLWIQL |
Full Sequence |
---|
Protein Sequence Length: 843 Download |
MVMEKVQGRG FLGVVFLVIV FLSVSSGEAQ SRSFLVNCGA NSSVNVDGRR WIGDLVPNDN 60 FTVSSPGVAA TDSTANGDSL YRTARIFDNG LNYTFSGVQG NYFVRLHFCP FPIENHNVNE 120 SLFSVVANGL KLLADFNVPG EISDKYLPLQ NSNSNSSSLS LVKEYILAIN DVLVVEFIPS 180 KGSFGFINAM EIVPVIGTLF ADLVRRVGGS DANVSGRGIE TMYRLNVGGQ EIKPDQDSDL 240 WRKWEVDSSY MITADAGVEI KNSSNVTYAS NNDSSVAPLL VYETARIMSN TEVLEKKFNM 300 SWKFEVDPDF DYLIRLHFCE LVYDKANQRI FKVYINNKTA ADNFDVYARS GGKNIAYHQD 360 YFDAISAKIN TLWIQLGPDT AVGAWGTDAL LNGLEIFKLS RSGNLAYGDR IGPTGKSASH 420 LKSWILWLGI GAGVASALII AIACTCIFCF CKSQRNEMSN TKDNPPGWRP LFMHGAVLSS 480 IANAKGGAQT LNGSVAAFTR VGRRFTLSEI RAATDNFDDS LVIGVGGFGK VYKGEIEDGT 540 LAAIKRSNPQ SEQGLAEFET EIEMLSKLRH RHLVSLIGFC DEQNEMILVY EFMANGTLRS 600 HLFGSGFPPL TWKQRLEACT GAARGLHYLH TGADRGIIHR DVKTTNILLD ENFVAKMADF 660 GLSKDGPALD HTHVSTAVKG SFGYLDPEYF RRQHLTEKSD VYSFGVVLFE VVCSRPVINP 720 SLPKDQINLA EWAMKWQRQR SLETIIDPRL RGNSCPESLK KFGEIAEKCL ADEGRNRPTM 780 GEVLWHLEYV LQLHEAWMRT NATETSITSS QALEDLELRV AEDAQRRPSS LDEDTVRPRH 840 EG* 900 |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam07714 | Pkinase_Tyr | 3.0e-50 | 522 | 787 | 274 | + Protein tyrosine kinase. | ||
smart00219 | TyrKc | 1.0e-51 | 522 | 787 | 274 | + Tyrosine kinase, catalytic domain. Phosphotransferases. Tyrosine-specific kinase subfamily. | ||
smart00221 | STYKc | 1.0e-52 | 522 | 787 | 277 | + Protein kinase; unclassified specificity. Phosphotransferases. The specificity of this class of kinases can not be predicted. Possible dual-specificity Ser/Thr/Tyr kinase. | ||
cd00192 | PTKc | 5.0e-53 | 522 | 788 | 283 | + Catalytic domain of Protein Tyrosine Kinases. Protein Tyrosine Kinase (PTK) family, catalytic domain. This PTKc family is part of a larger superfamily that includes the catalytic domains of protein serine/threonine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase (PI3K). PTKs catalyze the transfer of the gamma-phosphoryl group from ATP to tyrosine (tyr) residues in protein substrates. They can be classified into receptor and non-receptor tyr kinases. PTKs play important roles in many cellular processes including, lymphocyte activation, epithelium growth and maintenance, metabolism control, organogenesis regulation, survival, proliferation, differentiation, migration, adhesion, motility, and morphogenesis. Receptor tyr kinases (RTKs) are integral membrane proteins which contain an extracellular ligand-binding region, a transmembrane segment, and an intracellular tyr kinase domain. RTKs are usually activated through ligand binding, which causes dimerization and autophosphorylation of the intracellular tyr kinase catalytic domain, leading to intracellular signaling. Some RTKs are orphan receptors with no known ligands. Non-receptor (or cytoplasmic) tyr kinases are distributed in different intracellular compartments and are usually multi-domain proteins containing a catalytic tyr kinase domain as well as various regulatory domains such as SH3 and SH2. PTKs are usually autoinhibited and require a mechanism for activation. In many PTKs, the phosphorylation of tyr residues in the activation loop is essential for optimal activity. Aberrant expression of PTKs is associated with many development abnormalities and cancers. | ||
pfam12819 | Malectin_like | 4.0e-66 | 36 | 399 | 379 | + Carbohydrate-binding protein of the ER. Malectin is a membrane-anchored protein of the endoplasmic reticulum that recognises and binds Glc2-N-glycan. The domain is found on a number of plant receptor kinases. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0004672 | protein kinase activity |
GO:0005524 | ATP binding |
GO:0006468 | protein phosphorylation |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI31024.1 | 0 | 13 | 817 | 5 | 813 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002264211.1 | 0 | 3 | 817 | 40 | 858 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002299052.1 | 0 | 3 | 842 | 1 | 840 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002330599.1 | 0 | 3 | 832 | 1 | 836 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523186.1 | 0 | 3 | 842 | 1 | 842 | kinase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2qkw_B | 0 | 504 | 796 | 28 | 319 | A Chain A, Structural Basis For Activation Of Plant Immunity By Bacterial Effector Protein Avrpto |
PDB | 3hgk_D | 0 | 504 | 796 | 28 | 319 | E Chain E, Crystal Structure Of Effect Protein Avrptob Complexed With Kinase Pto |
PDB | 3hgk_C | 0 | 504 | 796 | 28 | 319 | E Chain E, Crystal Structure Of Effect Protein Avrptob Complexed With Kinase Pto |
PDB | 3hgk_B | 0 | 504 | 796 | 28 | 319 | E Chain E, Crystal Structure Of Effect Protein Avrptob Complexed With Kinase Pto |
PDB | 3hgk_A | 0 | 504 | 796 | 28 | 319 | E Chain E, Crystal Structure Of Effect Protein Avrptob Complexed With Kinase Pto |
Transmembrane Domains | ||||
---|---|---|---|---|
Start | End | |||
10 | 27 | |||
423 | 445 |
Signal Peptide | ||||
---|---|---|---|---|
Cleavage Site | ||||
29 |
EST Download unfiltered results here | ||||
---|---|---|---|---|
Hit | Length | Start | End | EValue |
ES805185 | 338 | 452 | 783 | 0 |
EX357602 | 257 | 527 | 783 | 0 |
DY971329 | 307 | 487 | 793 | 0 |
GT050217 | 319 | 502 | 820 | 0 |
ES795034 | 263 | 459 | 719 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
---|