| Basic Information | |
|---|---|
| Species | Populus trichocarpa |
| Cazyme ID | Potri.002G072300.1 |
| Family | GT47 |
| Protein Properties | Length: 461 Molecular Weight: 52764.6 Isoelectric Point: 9.3478 |
| Chromosome | Chromosome/Scaffold: 02 Start: 5002283 End: 5005248 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 85 | 383 | 0 |
| LSLKIYVYEEDEIDGLKELLRGRDGKISADACLKGQWGTQVKIHGLLLESRFRTRKKEEADLFFVPAYVKCVRMMGGLNDKEINHTYVKVLSQMPYFRRS GGRDHIFVFPSGAGAHLFRSWATYINRSIILTTEADRTDKKDTSAFNTWKDIIIPGNVEDGMTKRRIAMVQPLPLSKRKYLANYLGRAQGKVGRLKLIEL AKQYPDKLESPELKFSGPGKFGRMEYFQHLRNAKFCLAPRGESSWTLRFYESFFVECVPVILSDQAEFPFQNVIDYTQISIKWPSTRIGLELLEYLESI | |||
| Full Sequence |
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| Protein Sequence Length: 461 Download |
| MGSPNNKPAR IFSPHNHTSP PCTRTHQIGA LLLIATTFFL TRLFDQAFTT CPPSSLNNDH 60 SSPNVVHVSD GGSLSWPQRG YGSHLSLKIY VYEEDEIDGL KELLRGRDGK ISADACLKGQ 120 WGTQVKIHGL LLESRFRTRK KEEADLFFVP AYVKCVRMMG GLNDKEINHT YVKVLSQMPY 180 FRRSGGRDHI FVFPSGAGAH LFRSWATYIN RSIILTTEAD RTDKKDTSAF NTWKDIIIPG 240 NVEDGMTKRR IAMVQPLPLS KRKYLANYLG RAQGKVGRLK LIELAKQYPD KLESPELKFS 300 GPGKFGRMEY FQHLRNAKFC LAPRGESSWT LRFYESFFVE CVPVILSDQA EFPFQNVIDY 360 TQISIKWPST RIGLELLEYL ESIPDENIEQ MIAAGRQIRC LWVYAPEFES CSAMQGIMWE 420 LQRKVRQFHQ SAETFWLHNR TIVDRRLVEF SSWVPPMPLP * |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-45 | 87 | 383 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_564141.1 | 0 | 5 | 460 | 6 | 462 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002265632.1 | 0 | 1 | 460 | 1 | 459 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002300942.1 | 0 | 1 | 460 | 1 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002307477.1 | 0 | 1 | 460 | 1 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002526175.1 | 0 | 1 | 460 | 1 | 453 | catalytic, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| CX668832 | 291 | 147 | 437 | 0 |
| FE707914 | 279 | 127 | 405 | 0 |
| EH692645 | 270 | 164 | 433 | 0 |
| FE707913 | 274 | 188 | 461 | 0 |
| DY295548 | 349 | 1 | 346 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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