| Basic Information | |
|---|---|
| Species | Populus trichocarpa |
| Cazyme ID | Potri.002G238600.4 |
| Family | GT1 |
| Protein Properties | Length: 469 Molecular Weight: 52095.1 Isoelectric Point: 6.705 |
| Chromosome | Chromosome/Scaffold: 02 Start: 23153869 End: 23162082 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
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| Family | Start | End | Evalue |
| GT1 | 66 | 448 | 0 |
| VGTRGDVQPFIAIGKRLQDYGHRVRLATHSNFKEFVETAGLEFFPLGGDPKVLAGYMVKNKGFLPSGPSEISVQRNQIKEIIYSLLPACKEPDIDSGIPF KADAIIANPPAYGHTHVAEALKVPLHIFFTMPWTPTSEFPHPLSRVKQPAGYRLSYQIVDSLIWLGIRDMINDLRKKKLKLRPVTYLSGSQGSDSDVPHG YLWSPHLVPKPKDWGANIDVVGFCFLDLASNYEPPESLLKWLEAGQKPIYIGFGSLPVEEPEKMTQTIVEAVEQTGQRGIINKGWGGLGNLAEPKDFIYL LDNCPHDWLFLQCKAVVHHGGAGTTAAGLKAACPTTIVPFFGDQPFWGERVHARGVGPPPIPVDEFSRTKLIDAIIFMLDPKS | |||
| Full Sequence |
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| Protein Sequence Length: 469 Download |
| MQRKLLRRIA SVKHDGTVEF EVPGDVEPQA PGVGYDDVYN TVVDDEPLDA TDLQYIPPLQ 60 IVMLIVGTRG DVQPFIAIGK RLQDYGHRVR LATHSNFKEF VETAGLEFFP LGGDPKVLAG 120 YMVKNKGFLP SGPSEISVQR NQIKEIIYSL LPACKEPDID SGIPFKADAI IANPPAYGHT 180 HVAEALKVPL HIFFTMPWTP TSEFPHPLSR VKQPAGYRLS YQIVDSLIWL GIRDMINDLR 240 KKKLKLRPVT YLSGSQGSDS DVPHGYLWSP HLVPKPKDWG ANIDVVGFCF LDLASNYEPP 300 ESLLKWLEAG QKPIYIGFGS LPVEEPEKMT QTIVEAVEQT GQRGIINKGW GGLGNLAEPK 360 DFIYLLDNCP HDWLFLQCKA VVHHGGAGTT AAGLKAACPT TIVPFFGDQP FWGERVHARG 420 VGPPPIPVDE FSRTKLIDAI IFMLDPKSRS VPWISLRPWR MRMVPLEQ* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG1819 | COG1819 | 6.0e-30 | 61 | 448 | 394 | + Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms] | ||
| pfam03033 | Glyco_transf_28 | 2.0e-35 | 61 | 205 | 145 | + Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities. | ||
| cd03784 | GT1_Gtf_like | 2.0e-113 | 61 | 449 | 389 | + This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005975 | carbohydrate metabolic process |
| GO:0008152 | metabolic process |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| GO:0030259 | lipid glycosylation |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI37267.1 | 0 | 4 | 451 | 117 | 564 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002265023.1 | 0 | 4 | 451 | 164 | 611 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002301763.1 | 0 | 2 | 450 | 35 | 483 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002321244.1 | 0 | 2 | 450 | 50 | 497 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002521125.1 | 0 | 4 | 451 | 126 | 575 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3h4t_A | 5e-29 | 59 | 451 | 1 | 361 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| PDB | 3h4i_A | 5e-29 | 59 | 451 | 1 | 361 | A Chain A, Chimeric Glycosyltransferase For The Generation Of Novel Natural Products |
| PDB | 1rrv_B | 4e-22 | 59 | 450 | 1 | 374 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| PDB | 1rrv_A | 4e-22 | 59 | 450 | 1 | 374 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| PDB | 1iir_A | 1e-16 | 303 | 422 | 230 | 346 | A Chain A, Crystal Structure Of Udp-Glucosyltransferase Gtfb |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| GT046352 | 335 | 68 | 402 | 0 |
| GO883166 | 334 | 21 | 354 | 0 |
| DV466557 | 272 | 178 | 449 | 0 |
| GT046352 | 32 | 395 | 426 | 0.0008 |
| DV466557 | 19 | 446 | 464 | 2.4 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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