Basic Information | |
---|---|
Species | Populus trichocarpa |
Cazyme ID | Potri.003G018900.1 |
Family | GT24 |
Protein Properties | Length: 1664 Molecular Weight: 187484 Isoelectric Point: 5.5832 |
Chromosome | Chromosome/Scaffold: 03 Start: 2276102 End: 2300032 |
Description | UDP-glucose:glycoprotein glucosyltransferases;transferases, transferring hexosyl groups;transferases, transferring glycosyl groups |
View CDS |
External Links |
---|
NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT24 | 1337 | 1584 | 0 |
INIFSIASGHLYERFLKIMILSVWKNTQRPVKFWFIKNYLSPQFKDVIPHMAQEYGFEYELVTYKWPSWLHKQTEKQRIIWAYKILFLDVIFPLSLERVI FVDADQVVRADMGELYDMDIKGRPLAYTPFCDNNRDMDGYRFWSQGFWKEHLRGRPYHISALYIVDLVKFRETAAGDNLRVFYETLSKDPNSLSNLDQDL PNYAQHTVPIFSLPQEWLWCESWCGNATKSRAKTIDLCNNPMTKEPKL |
Full Sequence |
---|
Protein Sequence Length: 1664 Download |
MGTRFRSGSC VLVILVCVVG FCGFGSVSCG ENRRPKNVQV AVRAKWEGTP ILLEAGELLS 60 KERKDIYWEF IDSWLHSKKE DNDSYTAKDC LKKIMKHGHA LLSDTLASLF DFSLILRSAS 120 PRLVLYRQLA EESLSSFPLL DDSFSNNASG GLAKINDTNE MKRSDPLLVG RNPEIPGGKC 180 CWVDTGAALF YDVADLLLWL HSPTGMAEDS FQQPELFDFD HVHFESLSGS PVTILYGALG 240 TDCFKEFHSA LVEAAKQGKV KYVVRPVLPS GCESKVGRCV AVGASDSLNL GGYGVELALK 300 NMEYKAMDDS AIKKGVTLED PRTEDLSQEV RGFIFSKILE RKPELTSEIM AFRDYLLSST 360 ISDTLDVWEL KDLGHQTAQR IVHASDPLQS MQEINQNFPS VVSSLSRMKL KDSVKDEITA 420 NQRMIPPGKS LMALNGALIN IEDIDLYLLV DMVQQELSLA DQFSKLKVPH STIRKLLSTA 480 SPPESSMIRV DFRSSHVHYL NNLEEDAMYK RWRNNINEIL MPVFPGQLRY IRKNLFHAVY 540 VLDPATSCGL ESVDMILSLY ENNFPMRFGL ILYSSKFIKK ATSRGLHLSA EENDGETEED 600 ISSLIIRLFI YIKESYGTPT AFQFLSNVNR LRMESDSEDD VPETHHVDGA FVDTILPKVK 660 TPPQDILLKL AKEQTYKELS QESSMFVFKL GLNKLQCCLL MNGLVFDSSE EVLMNAMNDE 720 LPRIQEQVYY GQINSHTDVL DKFLSESGIG RYNPQIIAEG KAKPRFISLT SGVLGGKSVV 780 NDINFLHSPG TVDDVKPVTH LLAVDITSKK GINLLHEGIR YLIEGSKGAR LGVLFSSSQD 840 SDLPGLLLVK VFEITTASYS HKKSVLNFLE HLCSFYEQKY ILASSVAAES TQTFIDKVYD 900 LADANELPQK AYKSILSEFS ADKVKNQLNK VSQFFYLLLG LESGVNAVIT NGRVMFPGDE 960 GTFLSHDLHL LETMEFKQRV KHIGEIIEEV QWQDVDPDML TSKFVSDIIM YVSSAMAMRE 1020 RSSESARFEI LNAEHSAVII DNENSSVHID AVVDPLSAAG QKVSSLLRVL RKYVQPSMRI 1080 VLNPMSSLVD LPLKNYYRYV VPTMDDFSST DLTVNGPQAF FANMPLSKTL TMNLDVPEPW 1140 LVEPVIAVHD LDNILLENLG DTRTLQAVFE LEALVLTGHC SEKDHEPPRG LQLILGTKSN 1200 PHLVDTLVMA NLGYWQMKVS PGVWYLQLAP GRSSELYAFR EGGDGSQEKH LSKLITINDL 1260 RGKVVHLEVV KKKGMEHEKL LISSDDDNNS QRKGTHDSWN SNLFKWASGF IGGGGLSKKN 1320 ESALMEHEKS GRHGKTINIF SIASGHLYER FLKIMILSVW KNTQRPVKFW FIKNYLSPQF 1380 KDVIPHMAQE YGFEYELVTY KWPSWLHKQT EKQRIIWAYK ILFLDVIFPL SLERVIFVDA 1440 DQVVRADMGE LYDMDIKGRP LAYTPFCDNN RDMDGYRFWS QGFWKEHLRG RPYHISALYI 1500 VDLVKFRETA AGDNLRVFYE TLSKDPNSLS NLDQDLPNYA QHTVPIFSLP QEWLWCESWC 1560 GNATKSRAKT IDLCNNPMTK EPKLQGAKRI VSEWVNLDSE ARHFTAKILG DEVNPQELVS 1620 PNQSQAKILG DEVNPQELVS PNQSQDYQTD NSLEEDAESK SEL* |
Functional Domains Download unfiltered results here | ||||||
---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
cd06429 | GT8_like_1 | 0.001 | 1361 | 1459 | 105 | + GT8_like_1 represents a subfamily of GT8 with unknown function. A subfamily of glycosyltransferase family 8 with unknown function: Glycosyltransferase family 8 comprises enzymes with a number of known activities; lipopolysaccharide galactosyltransferase lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase and inositol 1-alpha-galactosyltransferase. It is classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. |
cd04194 | GT8_A4GalT_like | 3.0e-12 | 1337 | 1553 | 227 | + A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS. |
cd00505 | Glyco_transf_8 | 2.0e-55 | 1337 | 1584 | 257 | + Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+. |
pfam06427 | UDP-g_GGTase | 5.0e-79 | 1006 | 1211 | 212 | + UDP-glucose:Glycoprotein Glucosyltransferase. The N-terminal region of this group of proteins is required for correct folding of the ER UDP-Glc: glucosyltransferase. |
cd06432 | GT8_HUGT1_C_like | 2.0e-175 | 1337 | 1584 | 248 | + The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family. C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0003980 | UDP-glucose:glycoprotein glucosyltransferase activity |
GO:0006486 | protein glycosylation |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAG51883.1 | 0 | 3 | 1663 | 5 | 1674 | AC016162_4 putative UDP-glucose:glycoprotein glucosyltransferase; 101200-91134 [Arabidopsis thaliana] |
DDBJ | BAD28382.1 | 0 | 31 | 1616 | 33 | 1602 | putative UDP-glucose:glycoprotein glucosyltransferase [Oryza sativa Japonica Group] |
RefSeq | NP_177278.3 | 0 | 3 | 1663 | 5 | 1613 | EBS1 (EMS-mutagenized bri1 suppressor 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002268972.1 | 0 | 1 | 1663 | 1 | 1611 | PREDICTED: similar to EBS1 (EMS-MUTAGENIZED BRI1 SUPPRESSOR 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Vitis vinifera] |
RefSeq | XP_002529534.1 | 0 | 1 | 1534 | 1 | 1499 | UDP-glucose glycoprotein:glucosyltransferase, putative [Ricinus communis] |