Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.003G073500.1 |
Family | GT68 |
Protein Properties | Length: 528 Molecular Weight: 59914.6 Isoelectric Point: 6.3985 |
Chromosome | Chromosome/Scaffold: 03 Start: 10228395 End: 10232747 |
Description | O-fucosyltransferase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT68 | 209 | 502 | 0 |
NRVLVIPSSRFDYQYNRVLDIEHVNDCLGRKVVVTFEEFVEIMKNKPHIDRFFCYFSDPTPCYVDEEHVKKLKGLGVSMGKLESPWKEDIKKPSKLTVKD VEGKFVSDDNVIAVGDVFFADVEEEWIMQPGGPIAHKCKTLIEPTRIIMLTAQRFIQTFLGSNFIALHFRRHGFLKFCNAKKPSCFYPVPQAADCIARVV ERANAPVVYLSTDAAESETGLLQSLVVVNGRTVPLVTRPSRNAAEKWDALLYRHGLQEDAQVEAMLDKTICAMSSVFIGASGSTFTEDIFRLRK |
Full Sequence |
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Protein Sequence Length: 528 Download |
MERDSSDEED DREHLIEQND RKHHQNGRYS LFAAAIIFLP LFILFLSFST DIRNLFSTHL 60 KVGDSLSIRM RESELRALYL LKKQQLSLFS LWNSTGNSTL LEKDLNSVSF EDLKSALLKQ 120 ISLNKEIQQV LLAPHESGNV SSSSSDLDFS NAGGFVQRCE KVDQRFADRK TIEWKPKPNK 180 FLFALCLSGQ MSNHLICLEK HMFFAALLNR VLVIPSSRFD YQYNRVLDIE HVNDCLGRKV 240 VVTFEEFVEI MKNKPHIDRF FCYFSDPTPC YVDEEHVKKL KGLGVSMGKL ESPWKEDIKK 300 PSKLTVKDVE GKFVSDDNVI AVGDVFFADV EEEWIMQPGG PIAHKCKTLI EPTRIIMLTA 360 QRFIQTFLGS NFIALHFRRH GFLKFCNAKK PSCFYPVPQA ADCIARVVER ANAPVVYLST 420 DAAESETGLL QSLVVVNGRT VPLVTRPSRN AAEKWDALLY RHGLQEDAQV EAMLDKTICA 480 MSSVFIGASG STFTEDIFRL RKGWESASSC DEYLCQGELP NYIAENE* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd11548 | NodZ_like | 0.002 | 362 | 495 | 137 | + Alpha 1,6-fucosyltransferase similar to Bradyrhizobium NodZ. Bradyrhizobium NodZ is an alpha 1,6-fucosyltransferase involved in the biosynthesis of the nodulation factor, a lipo-chitooligosaccharide formed by three-to-six beta-1,4-linked N-acetyl-d-glucosamine (GlcNAc) residues and a fatty acid acyl group attached to the nitrogen atom at the non-reducing end. NodZ transfers L-fucose from the GDP-beta-L-fucose donor to the reducing residue of the chitin oligosaccharide backbone, before the attachment of a fatty acid group. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
cd11296 | O-FucT_like | 0.0003 | 181 | 215 | 35 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
pfam10250 | O-FucT | 0.0001 | 204 | 494 | 332 | + GDP-fucose protein O-fucosyltransferase. This is a family of conserved proteins representing the enzyme responsible for adding O-fucose to EGF (epidermal growth factor-like) repeats. Six highly conserved cysteines are present in O-FucT-1 as well as a DXD-like motif (ERD), conserved in mammals, Drosophila, and C. elegans. Both features are characteristic of several glycosyltransferase families. The enzyme is a membrane-bound protein released by proteolysis and, as for most glycosyltransferases, is strongly activated by manganese. | ||
cd11298 | O-FucT-2 | 3.0e-8 | 368 | 505 | 142 | + GDP-fucose protein O-fucosyltransferase 2. O-FucT-2 adds O-fucose to thrombospondin type 1 repeats (TSRs), and appears conserved in bilateria. The O-fucosylation of TSRs appears to play a role in regulating secretion of metalloproteases of the ADAMTS superfamily. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
cd11296 | O-FucT_like | 4.0e-17 | 343 | 501 | 169 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_173170.2 | 0 | 1 | 527 | 1 | 564 | unknown protein [Arabidopsis thaliana] |
RefSeq | NP_199853.1 | 0 | 1 | 527 | 1 | 566 | unknown protein [Arabidopsis thaliana] |
RefSeq | XP_002264087.1 | 0 | 1 | 527 | 1 | 559 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002303337.1 | 0 | 1 | 527 | 1 | 527 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002533327.1 | 0 | 1 | 527 | 1 | 565 | conserved hypothetical protein [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 4ap6_D | 0.009 | 368 | 494 | 277 | 383 | A Chain A, Crystal Structure Of Human Pofut2 E54a Mutant In Complex With Gdp- Fucose |
PDB | 4ap6_C | 0.009 | 368 | 494 | 277 | 383 | A Chain A, Crystal Structure Of Human Pofut2 E54a Mutant In Complex With Gdp- Fucose |
PDB | 4ap6_B | 0.009 | 368 | 494 | 277 | 383 | A Chain A, Crystal Structure Of Human Pofut2 E54a Mutant In Complex With Gdp- Fucose |
PDB | 4ap6_A | 0.009 | 368 | 494 | 277 | 383 | A Chain A, Crystal Structure Of Human Pofut2 E54a Mutant In Complex With Gdp- Fucose |
PDB | 4ap5_B | 0.01 | 368 | 494 | 263 | 369 | A Chain A, Crystal Structure Of Human Pofut2 |