Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.003G079000.1 |
Family | GT47 |
Protein Properties | Length: 539 Molecular Weight: 62303.9 Isoelectric Point: 10.14 |
Chromosome | Chromosome/Scaffold: 03 Start: 10698633 End: 10707019 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 202 | 487 | 0 |
LKVYIYPDGDKPIFHQPHLYGIYASEGWFMKFMEASREFVSRDPEKAHLFYLPYSARQLEVAVYVPNSHNLRPLSIFMRDYANMIAAKYPYWNRTHGRDH FLVACHDWGPYALTMHEELTKNTMKALCNADVSEGIFTAGQDVSLPETTIRSPKRPLRNVGGGIRVSQRPILAFFAGNLHGRVRPTLLKYWHNKDDDMKI YGPLPIGISRKMTYVQHMKSSKYCICPMGYEVNSPRIVEAIYYECVPVIIADNFVLPFNEVLDWSAFSVVVAEKDIPKLKEILLAI |
Full Sequence |
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Protein Sequence Length: 539 Download |
MIGNRELFGV VLMRELLWRC AWKKVDWRKL LFLGVVMTIV GVLVPTYAFP HTVNMWFLSP 60 PLAVSSYVSL NGSMQLREAL TEARVQQFPP VSAASVLSPN TTVPSKNKRA KVSRTRNSLL 120 KRRKKKSKEN DESKVVLPPP RSPIPPRMQR FIWSLSPNDA LIYAKREIEH APVVIDDPYL 180 SAHIFRNISV FKRSYELMET ILKVYIYPDG DKPIFHQPHL YGIYASEGWF MKFMEASREF 240 VSRDPEKAHL FYLPYSARQL EVAVYVPNSH NLRPLSIFMR DYANMIAAKY PYWNRTHGRD 300 HFLVACHDWG PYALTMHEEL TKNTMKALCN ADVSEGIFTA GQDVSLPETT IRSPKRPLRN 360 VGGGIRVSQR PILAFFAGNL HGRVRPTLLK YWHNKDDDMK IYGPLPIGIS RKMTYVQHMK 420 SSKYCICPMG YEVNSPRIVE AIYYECVPVI IADNFVLPFN EVLDWSAFSV VVAEKDIPKL 480 KEILLAIPLR RYLTMLANLK TVQKHFLWNP RPLRYDLFHM ILHSIWFSRL NHVQIPQS* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-70 | 202 | 487 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI23466.1 | 0 | 6 | 535 | 6 | 535 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_567512.2 | 0 | 7 | 534 | 10 | 532 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002269459.1 | 0 | 6 | 538 | 6 | 538 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002303362.1 | 0 | 153 | 538 | 1 | 386 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530666.1 | 0 | 12 | 538 | 1 | 528 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |