| Basic Information | |
|---|---|
| Species | Populus trichocarpa |
| Cazyme ID | Potri.003G162000.1 |
| Family | GT47 |
| Protein Properties | Length: 414 Molecular Weight: 47191.4 Isoelectric Point: 7.0775 |
| Chromosome | Chromosome/Scaffold: 03 Start: 17296689 End: 17300534 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 46 | 341 | 0 |
| RLKVYVYELPSKYNKKLLQKDPRCLNHMFAAEIFMHRFLLSSPVRTLNPEEADWFYTPIYPTCDLTPTGLPLPFNSPRMMRSAIQLLSSNWPYWNRTEGA DHFFVVPHDFGACFHYQEEKAIERGILPLLRRATLVQTFGQRNHVCLNEGSITIPPYAPPQKMQAHQIPLDTPRSIFVYFRGLFYDVNNDPEGGYYARGA RAAVWENFKNNPLFDISTDHPTTYYEDMQRAIFCLCPLGWAPWSPRLVEAVVFGCIPVIIADDIVLPFADAIPWEEIGVFVAEEDVPHLDTFLTSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 414 Download |
| MRVCLWFFVV VIVFGFGDGK NADQRLRTER ISGSAGDVLE DNPVGRLKVY VYELPSKYNK 60 KLLQKDPRCL NHMFAAEIFM HRFLLSSPVR TLNPEEADWF YTPIYPTCDL TPTGLPLPFN 120 SPRMMRSAIQ LLSSNWPYWN RTEGADHFFV VPHDFGACFH YQEEKAIERG ILPLLRRATL 180 VQTFGQRNHV CLNEGSITIP PYAPPQKMQA HQIPLDTPRS IFVYFRGLFY DVNNDPEGGY 240 YARGARAAVW ENFKNNPLFD ISTDHPTTYY EDMQRAIFCL CPLGWAPWSP RLVEAVVFGC 300 IPVIIADDIV LPFADAIPWE EIGVFVAEED VPHLDTFLTS IPPEVILRKQ RLLANPSMKR 360 AMLFPQPAQP GDAFHQILNG LARKLPHDRT VYLKPGQKVL NWTTGPAGDL KPW* 420 |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| pfam03016 | Exostosin | 6.0e-79 | 46 | 341 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAX33320.1 | 0 | 1 | 413 | 1 | 412 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
| RefSeq | NP_174064.1 | 0 | 10 | 413 | 9 | 412 | GUT2; catalytic/ glucuronoxylan glucuronosyltransferase [Arabidopsis thaliana] |
| RefSeq | XP_002284685.1 | 0 | 1 | 413 | 1 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002297880.1 | 0 | 1 | 413 | 1 | 412 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002304637.1 | 0 | 1 | 413 | 1 | 413 | predicted protein [Populus trichocarpa] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
