Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.005G147500.1 |
Family | GT47 |
Protein Properties | Length: 426 Molecular Weight: 49033 Isoelectric Point: 9.2017 |
Chromosome | Chromosome/Scaffold: 05 Start: 12994853 End: 12999194 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 101 | 378 | 0 |
ERNFKIFIYPDGDPNTFYQTPRKLTGKYASEGYFFQNIRESRFQTQDPDQAHLFFIPISCHKMRGKGISYENMTIIVDNYVESLKSKYPYWNRTLGADHF FVTCHDVGVRATEGVPFLIKNAIRVVCSPSYDVGFIPHKDIALPQVLQPFALPAGGNDVEKRTTLGFWAGHRNSRIRVILARVWENDTELDISNNRINRA TGHLVYQKRFYGSKYCICPGGSQVNSARIADSIHYGCIPVILSNYYDLPFNDILDWHKFSVILKEQDVYRLKQILKDI |
Full Sequence |
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Protein Sequence Length: 426 Download |
MTAGKLSQQL QQQQQVQQSM CSLKGSLRTL AILTLVSFTY LSFNSLHSSY FSSSSSISAS 60 SVSLAPATKK TTILVKDYDD DEISDLYHSP RVFKLNYEEM ERNFKIFIYP DGDPNTFYQT 120 PRKLTGKYAS EGYFFQNIRE SRFQTQDPDQ AHLFFIPISC HKMRGKGISY ENMTIIVDNY 180 VESLKSKYPY WNRTLGADHF FVTCHDVGVR ATEGVPFLIK NAIRVVCSPS YDVGFIPHKD 240 IALPQVLQPF ALPAGGNDVE KRTTLGFWAG HRNSRIRVIL ARVWENDTEL DISNNRINRA 300 TGHLVYQKRF YGSKYCICPG GSQVNSARIA DSIHYGCIPV ILSNYYDLPF NDILDWHKFS 360 VILKEQDVYR LKQILKDIPD NKLVSLHKNL VKVQKHFQWN SPPVKYDAFH MVMYDLWLRH 420 HVIKY* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-55 | 100 | 378 | 298 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACU18220.1 | 0 | 17 | 425 | 5 | 409 | unknown [Glycine max] |
RefSeq | NP_195517.1 | 0 | 20 | 425 | 19 | 425 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002266299.1 | 0 | 12 | 425 | 8 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002307304.1 | 0 | 20 | 425 | 1 | 406 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002522880.1 | 0 | 1 | 425 | 1 | 406 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
JG847451 | 274 | 76 | 349 | 0 |
EH770778 | 275 | 116 | 390 | 0 |
GO268625 | 269 | 100 | 368 | 0 |
EX317869 | 278 | 125 | 402 | 0 |
EG459159 | 264 | 163 | 426 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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