| Basic Information | |
|---|---|
| Species | Populus trichocarpa |
| Cazyme ID | Potri.005G187400.1 |
| Family | GT47 |
| Protein Properties | Length: 461 Molecular Weight: 52877.7 Isoelectric Point: 9.4481 |
| Chromosome | Chromosome/Scaffold: 05 Start: 20482421 End: 20485342 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
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| Family | Start | End | Evalue |
| GT47 | 86 | 383 | 0 |
| SLKIYVYEEDEIDGLKELLRGREGKISADACVKGQWGTQVKIHRLLLQSRFRTRKKGEANLFFVPAYAKCVRMMGGLNDKEINHTYVKALSQMPYFRRSG GRDHIFVFPSGAGAHLFRSWATYINRSIILSPEGDRTDKKDTSSFNTWKDIIIPGNVEDGMTKRGAAMAQPLPLSKRKYLANYLGRAQGKVGRLKLIELA KQYPDKLECPELKFSGPEKFGRMEYFQHLRNAKFCVAPRGESSWTLRFYESFFVECVPVILSDQAEFPFQNVIDYTQISIKWPSTRIGLELLEYLESI | |||
| Full Sequence |
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| Protein Sequence Length: 461 Download |
| MGSPNNRPTR IFSSHHHNTP PCTRSHQIGA LLLVASTFFL TRLFDHPFST CPPSSLNHDH 60 TSQNVVHFSD GGYLSWPQMG YGTHLSLKIY VYEEDEIDGL KELLRGREGK ISADACVKGQ 120 WGTQVKIHRL LLQSRFRTRK KGEANLFFVP AYAKCVRMMG GLNDKEINHT YVKALSQMPY 180 FRRSGGRDHI FVFPSGAGAH LFRSWATYIN RSIILSPEGD RTDKKDTSSF NTWKDIIIPG 240 NVEDGMTKRG AAMAQPLPLS KRKYLANYLG RAQGKVGRLK LIELAKQYPD KLECPELKFS 300 GPEKFGRMEY FQHLRNAKFC VAPRGESSWT LRFYESFFVE CVPVILSDQA EFPFQNVIDY 360 TQISIKWPST RIGLELLEYL ESIPDEDVER MIAAGRQVRC LWVYAPELEL CSAMQGIMWE 420 LQRKVRQFHQ SAETFWLHNR TIVNRNMVEF SSWKPPMPLP * |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00869 | PI3Ka_II | 0.009 | 329 | 391 | 65 | + Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases phosphorylate phosphoinositol (PtdIns), PtdIns(4)-phosphate, but not PtdIns(4,5)-bisphosphate. They are larger, having a C2 domain at the C-terminus. | ||
| pfam03016 | Exostosin | 5.0e-45 | 87 | 383 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
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| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_564141.1 | 0 | 1 | 460 | 1 | 462 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002265632.1 | 0 | 1 | 460 | 1 | 459 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002300942.1 | 0 | 1 | 460 | 1 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002307477.1 | 0 | 1 | 460 | 1 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002526175.1 | 0 | 1 | 460 | 1 | 453 | catalytic, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| CX668832 | 291 | 147 | 437 | 0 |
| FE707914 | 279 | 127 | 405 | 0 |
| DY295548 | 349 | 1 | 346 | 0 |
| FE707913 | 274 | 188 | 461 | 0 |
| DY295548 | 56 | 295 | 347 | 0.032 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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