| Basic Information | |
|---|---|
| Species | Populus trichocarpa |
| Cazyme ID | Potri.006G047000.3 |
| Family | CE1 |
| Protein Properties | Length: 211 Molecular Weight: 23355.5 Isoelectric Point: 8.4174 |
| Chromosome | Chromosome/Scaffold: 06 Start: 3331641 End: 3334923 |
| Description | S-formylglutathione hydrolase |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| CE1 | 25 | 190 | 4.60004e-41 |
| SPTLGCSMTFYIYFPPSPSPSHKFPVLYWLSGLSCTDENFIAKSGAQRVASTEGIVLIAPDTSPRGLNVEGEADSWDFGVGAGFYLNATQEKWKNWRMYD YVVKELPKLLSENFPQLETSKASIFGHSMGGHGALTIYLKNLDKYKSVSAFSPVANPINCPWGQKA | |||
| Full Sequence |
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| Protein Sequence Length: 211 Download |
| METKPSEISS SKMFGGYNKR YKHFSPTLGC SMTFYIYFPP SPSPSHKFPV LYWLSGLSCT 60 DENFIAKSGA QRVASTEGIV LIAPDTSPRG LNVEGEADSW DFGVGAGFYL NATQEKWKNW 120 RMYDYVVKEL PKLLSENFPQ LETSKASIFG HSMGGHGALT IYLKNLDKYK SVSAFSPVAN 180 PINCPWGQKA FTNYLGPSKA DWEVKISSDT * |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam00756 | Esterase | 1.0e-39 | 25 | 191 | 168 | + Putative esterase. This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family. | ||
| COG0627 | COG0627 | 2.0e-54 | 1 | 201 | 217 | + Predicted esterase [General function prediction only] | ||
| TIGR02821 | fghA_ester_D | 1.0e-90 | 8 | 202 | 196 | + S-formylglutathione hydrolase. This model describes a protein family from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC 3.1.2.12). Members in eukaryotes such as the human protein are better known as esterase D (EC 3.1.1.1), an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well [Cellular processes, Detoxification]. | ||
| PLN02442 | PLN02442 | 2.0e-150 | 1 | 203 | 203 | + S-formylglutathione hydrolase | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004091 | carboxylesterase activity |
| GO:0016023 | cytoplasmic membrane-bounded vesicle |
| GO:0018738 | S-formylglutathione hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACJ11734.1 | 0 | 1 | 203 | 1 | 203 | S-formylglutathione hydrolase [Gossypium hirsutum] |
| GenBank | ACU18661.1 | 0 | 1 | 203 | 1 | 203 | unknown [Glycine max] |
| GenBank | ACU19052.1 | 0 | 1 | 203 | 1 | 203 | unknown [Glycine max] |
| RefSeq | XP_002284489.1 | 0 | 1 | 203 | 1 | 203 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
| RefSeq | XP_002308013.1 | 0 | 1 | 203 | 1 | 203 | esterase d, s-formylglutathione hydrolase [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3s8y_A | 0 | 8 | 203 | 7 | 200 | A Chain A, Bromide Soaked Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_B | 0 | 8 | 203 | 7 | 200 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_A | 0 | 8 | 203 | 7 | 200 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3fcx_B | 0 | 7 | 204 | 5 | 201 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3fcx_A | 0 | 7 | 204 | 5 | 201 | A Chain A, Crystal Structure Of Human Esterase D |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| formaldehyde oxidation II (glutathione-dependent) | S-FORMYLGLUTATHIONE-HYDROLASE-RXN | EC-3.1.2.12 | S-formylglutathione hydrolase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| CX184972 | 203 | 1 | 203 | 0 |
| DT524931 | 203 | 1 | 203 | 0 |
| AJ767078 | 203 | 1 | 203 | 0 |
| DT490294 | 203 | 1 | 203 | 0 |
| AJ769362 | 203 | 1 | 203 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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