Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.006G047000.4 |
Family | CE1 |
Protein Properties | Length: 234 Molecular Weight: 26358.5 Isoelectric Point: 9.5078 |
Chromosome | Chromosome/Scaffold: 06 Start: 3331641 End: 3334923 |
Description | S-formylglutathione hydrolase |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
CE1 | 25 | 173 | 1.3e-35 |
SPTLGCSMTFYIYFPPSPSPSHKFPVLYWLSGLSCTDENFIAKSGAQRVASTEGIVLIAPDTSPRGLNVEGEADSWDFGVGAGFYLNATQEKWKNWRMYD YVVKELPKLLSENFPQLETSKASIFGHSMGGHGALTIYLKNLDKYKVVG |
Full Sequence |
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Protein Sequence Length: 234 Download |
METKPSEISS SKMFGGYNKR YKHFSPTLGC SMTFYIYFPP SPSPSHKFPV LYWLSGLSCT 60 DENFIAKSGA QRVASTEGIV LIAPDTSPRG LNVEGEADSW DFGVGAGFYL NATQEKWKNW 120 RMYDYVVKEL PKLLSENFPQ LETSKASIFG HSMGGHGALT IYLKNLDKYK VVGHSYSLNI 180 LSRYLPSHQL PTQLIVHGAR RLSQIILDPV KLIGRNMMPL LWCQRSMMYL LPF* 240 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam12695 | Abhydrolase_5 | 0.0008 | 141 | 200 | 61 | + Alpha/beta hydrolase family. This family contains a diverse range of alpha/beta hydrolase enzymes. | ||
pfam00756 | Esterase | 4.0e-29 | 25 | 179 | 157 | + Putative esterase. This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family. | ||
COG0627 | COG0627 | 4.0e-43 | 1 | 174 | 181 | + Predicted esterase [General function prediction only] | ||
TIGR02821 | fghA_ester_D | 1.0e-68 | 8 | 172 | 166 | + S-formylglutathione hydrolase. This model describes a protein family from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC 3.1.2.12). Members in eukaryotes such as the human protein are better known as esterase D (EC 3.1.1.1), an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well [Cellular processes, Detoxification]. | ||
PLN02442 | PLN02442 | 4.0e-123 | 1 | 172 | 172 | + S-formylglutathione hydrolase |
Gene Ontology | |
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GO Term | Description |
GO:0004091 | carboxylesterase activity |
GO:0016023 | cytoplasmic membrane-bounded vesicle |
GO:0018738 | S-formylglutathione hydrolase activity |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACJ11734.1 | 0 | 1 | 170 | 1 | 170 | S-formylglutathione hydrolase [Gossypium hirsutum] |
GenBank | ACU18661.1 | 0 | 1 | 172 | 1 | 172 | unknown [Glycine max] |
GenBank | ACU19052.1 | 0 | 1 | 172 | 1 | 172 | unknown [Glycine max] |
RefSeq | XP_002284489.1 | 0 | 1 | 172 | 1 | 172 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
RefSeq | XP_002308013.1 | 0 | 1 | 172 | 1 | 172 | esterase d, s-formylglutathione hydrolase [Populus trichocarpa] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3fcx_B | 0 | 7 | 172 | 5 | 169 | A Chain A, Crystal Structure Of Human Esterase D |
PDB | 3fcx_A | 0 | 7 | 172 | 5 | 169 | A Chain A, Crystal Structure Of Human Esterase D |
PDB | 3s8y_A | 0 | 8 | 172 | 7 | 169 | A Chain A, Bromide Soaked Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
PDB | 3i6y_B | 0 | 8 | 172 | 7 | 169 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
PDB | 3i6y_A | 0 | 8 | 172 | 7 | 169 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
formaldehyde oxidation II (glutathione-dependent) | S-FORMYLGLUTATHIONE-HYDROLASE-RXN | EC-3.1.2.12 | S-formylglutathione hydrolase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
CX170182 | 195 | 1 | 195 | 0 |
DT503215 | 172 | 1 | 172 | 0 |
DT503215 | 53 | 182 | 234 | 0 |
DT490294 | 172 | 1 | 172 | 0 |
DT490294 | 53 | 182 | 234 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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