| Basic Information | |
|---|---|
| Species | Populus trichocarpa |
| Cazyme ID | Potri.006G064600.1 |
| Family | GT47 |
| Protein Properties | Length: 349 Molecular Weight: 40798.1 Isoelectric Point: 8.6035 |
| Chromosome | Chromosome/Scaffold: 06 Start: 4744764 End: 4747873 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 17 | 299 | 0 |
| KRFKIWVYREGETPMVHNGPMKHIYSIEGQFIDEMESGKSPFLARNHDEAHAFFLPISVAYIVEFVYLPITTYHRERLVRIFKDYVTVVANKYPYWNRSR GGDHFMVSCHDWAPQVSRDDPELYKNLIRVMCNANTSEGFRPRRDATLPELNCPPLKLTPACRGLAPHERKIFAFFAGGAHGDIRKILLRHWKEKDDEIQ VHEYLPKDQDYMELMGQSKFCLCPSGFEVASPRVAESIYSGCVPVIISDHYNLPFSDVLDWSQFSVQIPVEKIPEIKTILRGI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 349 Download |
| MYRNAYAFHQ SYSEMVKRFK IWVYREGETP MVHNGPMKHI YSIEGQFIDE MESGKSPFLA 60 RNHDEAHAFF LPISVAYIVE FVYLPITTYH RERLVRIFKD YVTVVANKYP YWNRSRGGDH 120 FMVSCHDWAP QVSRDDPELY KNLIRVMCNA NTSEGFRPRR DATLPELNCP PLKLTPACRG 180 LAPHERKIFA FFAGGAHGDI RKILLRHWKE KDDEIQVHEY LPKDQDYMEL MGQSKFCLCP 240 SGFEVASPRV AESIYSGCVP VIISDHYNLP FSDVLDWSQF SVQIPVEKIP EIKTILRGIS 300 YDEYLKMQKG VMKVQRHFVL NRPAKPYDVL HMVLHSVWLR RLNIRVPH* |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| pfam00534 | Glycos_transf_1 | 0.0007 | 177 | 270 | 95 | + Glycosyl transferases group 1. Mutations in this domain of human PIGA lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family. |
| pfam03016 | Exostosin | 5.0e-69 | 15 | 299 | 303 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI25537.1 | 0 | 1 | 348 | 125 | 477 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002263848.1 | 0 | 1 | 348 | 44 | 396 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002331028.1 | 0 | 15 | 348 | 1 | 334 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002331029.1 | 0 | 15 | 347 | 1 | 335 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002531944.1 | 0 | 16 | 346 | 1 | 363 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
