Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.006G064800.1 |
Family | GT47 |
Protein Properties | Length: 513 Molecular Weight: 58587.3 Isoelectric Point: 9.5454 |
Chromosome | Chromosome/Scaffold: 06 Start: 4758902 End: 4763000 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 175 | 464 | 0 |
EKRFKVWIYKEGELPVVHGGPVNDIYSIEGQFLDEMESGKSQFIARHPEEAQAFLLPVSVAYIIHYVYRPRITFSRDQLQRLVTDYVRVIADKHPYWNRT HGADHFSVSCHDWAPDVSRANPGLFKYFIRALCNANTSEGFQPQRDVSIPEIFLPVGKLGPPQEYAQPPSKRSILAFFAGGAHGHIRKILLERWKEKDDE IQVHEYLTQKNKKNNNLYFELMGQSKFCLCPSGHEVASPRVVTAIQLGCVPVTISDNYSLPFSDVLDWSKFSVDIPSEKIPDIKIILKGI |
Full Sequence |
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Protein Sequence Length: 513 Download |
MATLSCSPLS FLLLAALVST LFFVCLSPFN YQTIKVSSRL SSFYTYNYTF ERLQPLPSPV 60 ALQPPPNTTV GDDQEITNWR NKGKISERLQ PSPAPISLPV QNSSVVFSGP GIPVITRHEK 120 TGFERIEEGL AIARAAIYKA VRSQNSSSYK KGSYVPRGAM YRNQYAFHQS YEEMEKRFKV 180 WIYKEGELPV VHGGPVNDIY SIEGQFLDEM ESGKSQFIAR HPEEAQAFLL PVSVAYIIHY 240 VYRPRITFSR DQLQRLVTDY VRVIADKHPY WNRTHGADHF SVSCHDWAPD VSRANPGLFK 300 YFIRALCNAN TSEGFQPQRD VSIPEIFLPV GKLGPPQEYA QPPSKRSILA FFAGGAHGHI 360 RKILLERWKE KDDEIQVHEY LTQKNKKNNN LYFELMGQSK FCLCPSGHEV ASPRVVTAIQ 420 LGCVPVTISD NYSLPFSDVL DWSKFSVDIP SEKIPDIKII LKGISVRRYL TMQRRVMQIR 480 RHFTLNRPAQ PYDMLHMILH SVWLRRLDVK LP* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-61 | 174 | 464 | 308 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_002308053.1 | 0 | 174 | 512 | 1 | 339 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002308055.1 | 0 | 174 | 512 | 1 | 338 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324627.1 | 0 | 174 | 510 | 1 | 337 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002331030.1 | 0 | 174 | 512 | 1 | 339 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002531945.1 | 0 | 87 | 512 | 48 | 451 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |