Basic Information | |
---|---|
Species | Populus trichocarpa |
Cazyme ID | Potri.006G064900.1 |
Family | GT47 |
Protein Properties | Length: 495 Molecular Weight: 56808.7 Isoelectric Point: 10.3023 |
Chromosome | Chromosome/Scaffold: 06 Start: 4765561 End: 4768575 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 158 | 446 | 0 |
EKRFKIWVYKEGELPVLHGGPVNNIYSVEGQFLDEIERGKSNFIARHPDEAHAFLLPLSVAYIMHYIYKPRVTFSRHQLQTLVTDYVRVIADKYTYWNRT NGADHFSISCHDWGPDISRANPELFKYFIRALCNANTSEGFQPQRDVSVPEIFLHVGKLGLPREGAQPPSKRPILAFFAGGAHGRIRKVLLKRWKDKDGE IQVHEYVTQRKKNNNLYFKLMGQSKFCLCPSGHEVASPRVVTAIQLGCVPVIISDNYSLPFSDVLDWSKFSVNIPSEKIQEIKTILKGI |
Full Sequence |
---|
Protein Sequence Length: 495 Download |
MATFLSSPIN CLLQSAFLST LLLVCLSPFY QPINISSRLS SFYTPNFQPY PSTILLLPPP 60 NTTLGVGQDA QITWKIKVSP FDERLRPSRS PVLLAVQNIT KIKTGFERIE DGLARARDAI 120 LRAIRSRNSS SYKKGSYVPR GVIYRNQYAF HQSHTEMEKR FKIWVYKEGE LPVLHGGPVN 180 NIYSVEGQFL DEIERGKSNF IARHPDEAHA FLLPLSVAYI MHYIYKPRVT FSRHQLQTLV 240 TDYVRVIADK YTYWNRTNGA DHFSISCHDW GPDISRANPE LFKYFIRALC NANTSEGFQP 300 QRDVSVPEIF LHVGKLGLPR EGAQPPSKRP ILAFFAGGAH GRIRKVLLKR WKDKDGEIQV 360 HEYVTQRKKN NNLYFKLMGQ SKFCLCPSGH EVASPRVVTA IQLGCVPVII SDNYSLPFSD 420 VLDWSKFSVN IPSEKIQEIK TILKGISHKR YLTMQRRVIQ AQRHFTLNRP AKPYDMIHMI 480 LHSIWLRRLN HRMP* |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-63 | 157 | 446 | 307 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_002308053.1 | 0 | 157 | 494 | 1 | 339 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002308055.1 | 0 | 157 | 494 | 1 | 338 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324627.1 | 0 | 157 | 490 | 1 | 335 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002331030.1 | 0 | 157 | 494 | 1 | 339 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002531945.1 | 0 | 66 | 494 | 30 | 451 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
---|---|---|---|
Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
EST Download unfiltered results here | ||||
---|---|---|---|---|
Hit | Length | Start | End | EValue |
CV281186 | 223 | 274 | 495 | 0 |
EC939466 | 299 | 101 | 394 | 0 |
FD507587 | 233 | 200 | 432 | 0 |
CO983212 | 236 | 259 | 493 | 0 |
CV242175 | 204 | 288 | 490 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
---|