Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.006G118000.2 |
Family | GT47 |
Protein Properties | Length: 511 Molecular Weight: 57656.2 Isoelectric Point: 8.7152 |
Chromosome | Chromosome/Scaffold: 06 Start: 9313854 End: 9318456 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 173 | 454 | 0 |
EKQFKVFVYGEGEPPVFHNGPCRSIYSMEGNFIHRMEIDGHFRTKDPDKAHVYFLPFSVAMMVRFVYERESRDFGPIRRTVSDYINLISGKYPFWNRSLG ADHFMLACHDWGPEASFSVPHLGKISIRALCNANTSEKFNPIKDVSLPEINLRTGSIKGFVGGLSPSKRSILAFFAGRLHGPIRPVVLEHWENKDDDIKV HQQLPKGVSYYEMMRGSKFCLCPSGYEVASPRIVEALYAGCVPVLISDHYVPPFSDVLNWKSFSVEVPVSDIPSLKKILTSI |
Full Sequence |
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Protein Sequence Length: 511 Download |
MKLMVLMVPL ILVSGFVVIF GLRSTTTSSW DFIARQPAWL WWGHGNSSLN GASSVTVHAK 60 ESDESPPLIN GFSPPPQAVE ALPFEEPNVL KQDVSETSGP IAAPANEALD LARKTRHKTE 120 HTSLEKLEAG LQKARVALKE AKNGKQADDP DYAPAGPMYW NAEVFHRSYL EMEKQFKVFV 180 YGEGEPPVFH NGPCRSIYSM EGNFIHRMEI DGHFRTKDPD KAHVYFLPFS VAMMVRFVYE 240 RESRDFGPIR RTVSDYINLI SGKYPFWNRS LGADHFMLAC HDWGPEASFS VPHLGKISIR 300 ALCNANTSEK FNPIKDVSLP EINLRTGSIK GFVGGLSPSK RSILAFFAGR LHGPIRPVVL 360 EHWENKDDDI KVHQQLPKGV SYYEMMRGSK FCLCPSGYEV ASPRIVEALY AGCVPVLISD 420 HYVPPFSDVL NWKSFSVEVP VSDIPSLKKI LTSISPRQYI RMQRRVLQVR RHFEVNSPPK 480 RFDVFHMILH SIWLRRLNVG IHDDQLAITS * |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-65 | 172 | 454 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAB08605.1 | 0 | 93 | 503 | 3 | 407 | unnamed protein product [Arabidopsis thaliana] |
RefSeq | NP_001031828.1 | 0 | 93 | 503 | 113 | 517 | unknown protein [Arabidopsis thaliana] |
RefSeq | XP_002284018.1 | 0 | 172 | 502 | 1 | 331 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002326234.1 | 0 | 172 | 499 | 1 | 328 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002528630.1 | 0 | 92 | 510 | 159 | 574 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |