Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.006G238900.1 |
Family | GT47 |
Protein Properties | Length: 732 Molecular Weight: 82627.1 Isoelectric Point: 8.1538 |
Chromosome | Chromosome/Scaffold: 06 Start: 24806236 End: 24809541 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 400 | 682 | 0 |
EKMLKVYVYQDGEKPIFHQPILDGIYASEGWFMKHMEANENFVTKDPGKAHLFYLPFSSRLLELTLYVRHSHSRTNLIEYMRNYAGMIAAKYHFWNRTGG ADHFVAACHDWAPAETRGPLLNCIRALCNADIEVGFSIGKDVSLPETYVRSAQNPLKNLEGNPPSQRPILAFFAGNMHGYVRPVLLDYWGNKDPDMKIFG PMPHVKGNTNYIQHMKSSKFCICPRGHEVNSPRIVEAIFLECVPVIISDNFVPPFFEVLDWESFAVIVLEKDIPNLKNILVSI |
Full Sequence |
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Protein Sequence Length: 732 Download |
MPRRFCFGSK IGIYFLTELA FGIVFTIFVL KLDFWSFCGA DRTYFGDPFV WIRSPLRFMD 60 QGYQLLCLAK ARRLLFLVGA TVAIVIVVQY LEFPSSRVLV SLFSAVNTRS FMSRNSSTGS 120 EALGNMTLSN GLNTTNTGIL HETTDSDEAS DDKKETAEVN KSEEKEGSPN NSNASESKRG 180 SSDSFGLVSN ETISDDLANQ DKNSTLNTIN GSEEEKAMAP DASYINVDKD IAPISGRNKS 240 SDADPGYPSS APPMMNTFSN KTFSTDENSS PMIFESSNTT SMRKDTAGAL KRDENSGLLP 300 NNYSMSTSGS FSSKVTAAKR KTSKKPPSRV ISIHQMNELL RQSHASSSSV RPLWPSGVDQ 360 EMLFAKSQIE NAPLIKNETR LYAPIYRNVS MFRRSYELME KMLKVYVYQD GEKPIFHQPI 420 LDGIYASEGW FMKHMEANEN FVTKDPGKAH LFYLPFSSRL LELTLYVRHS HSRTNLIEYM 480 RNYAGMIAAK YHFWNRTGGA DHFVAACHDW APAETRGPLL NCIRALCNAD IEVGFSIGKD 540 VSLPETYVRS AQNPLKNLEG NPPSQRPILA FFAGNMHGYV RPVLLDYWGN KDPDMKIFGP 600 MPHVKGNTNY IQHMKSSKFC ICPRGHEVNS PRIVEAIFLE CVPVIISDNF VPPFFEVLDW 660 ESFAVIVLEK DIPNLKNILV SISEEKYIEM HKRVKKVQQH FLWHSKPEKY DLFHMILHSV 720 WYNRIFRIRP A* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-67 | 399 | 682 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_002280595.1 | 0 | 59 | 730 | 1 | 662 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002281263.1 | 0 | 59 | 729 | 1 | 667 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002283936.1 | 0 | 326 | 730 | 2 | 409 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309546.1 | 0 | 305 | 731 | 1 | 417 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002516500.1 | 0 | 285 | 731 | 12 | 456 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |